DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Vha16-3 and Atp6v0c

DIOPT Version :9

Sequence 1:	NP_001189086.1	Gene:	Vha16-3 / 317846	FlyBaseID:	FBgn0028667	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_001348460.1	Gene:	Atp6v0c / 11984	MGIID:	88116	Length:	214	Species:	Mus musculus

Alignment Length:	157	Identity:	126/157 - (80%)
Similarity:	141/157 - (89%)	Gaps:	1/157 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TDAAD-KDKPAYSFFFGSMGAASAIIFSALGAAYGTAKSGTGIAAMAVMRPELIMKSIIPVVMAG 66
            :|.|| |:.|.||.|||.|||:||::|||:||||||||||||||||:||||||||||||||||||
Mouse    58 SDMADIKNNPEYSSFFGVMGASSAMVFSAMGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAG 122

  Fly    67 IIAIYGLVVSVLIAGSLSDSYTIRKGYIHLAAGLSVGFAGLAAGFAIGIVGDAGVRGTAQQPRLF 131
            |||||||||:||||.||:|..|:.:.::.|.||||||.:||||||||||||||||||||||||||
Mouse   123 IIAIYGLVVAVLIANSLTDGITLYRSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLF 187

  Fly   132 VGMILILIFAEVLGLYGLIVAIYLYTK 158
            |||||||||||||||||||||:.|.||
Mouse   188 VGMILILIFAEVLGLYGLIVALILSTK 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha16-3	NP_001189086.1	V_ATP_synt_C	16..121	CDD:130170	83/104 (80%)
Vha16-3	NP_001189086.1	ATP-synt_Vo_c_ATP6C_rpt2	91..156	CDD:349416	54/64 (84%)
Atp6v0c	NP_001348460.1	V_ATP_synt_C	72..177	CDD:130170	83/104 (80%)
Atp6v0c	NP_001348460.1	ATP-synt_C	152..211	CDD:306615	54/58 (93%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834104
Domainoid	1	1.000	109	1.000	Domainoid score	I6373
eggNOG	1	0.900	-	-		E1_COG0636
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68199
Inparanoid	1	1.050	238	1.000	Inparanoid score	I3359
Isobase	1	0.950	-	0	Normalized mean entropy	S170
OMA	1	1.010	-	-		QHG53914
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001101
OrthoInspector	1	1.000	-	-		otm42564
orthoMCL	1	0.900	-	-		OOG6_100711
Panther	1	1.100	-	-	O	PTHR10263
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X666
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.710