DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Elo68alpha and ELOVL7

DIOPT Version :9

Sequence 1:	NP_729666.2	Gene:	Elo68alpha / 317841	FlyBaseID:	FBgn0052072	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001098028.1	Gene:	ELOVL7 / 79993	HGNCID:	26292	Length:	281	Species:	Homo sapiens

Alignment Length:	242	Identity:	89/242 - (36%)
Similarity:	134/242 - (55%)	Gaps:	5/242 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 DERTRNWPLVDSFWTVPVLLSIYLLMV-RYAPKWTTRHKPLQLRAPLFCHSLAMVFLNGYICLEL 79
            |.|..:|.|:.|.....:||..|:..| ...||.....||.:|:..:..::..:|..:.|:|.|.
Human    22 DPRVEDWLLMSSPLPQTILLGFYVYFVTSLGPKLMENRKPFELKKAMITYNFFIVLFSVYMCYEF 86

  Fly    80 YAATRDLDYNFGCQPCRVSFDPHEMRLTKAFWWFYISKILEFADTAFFILRQKWSQLSFLHVYHH 144
            ..:...:.|:|.|.....|..|..:|:.:..|.:|.||.:|..||.||:||:|.||::||||:||
Human    87 VMSGWGIGYSFRCDIVDYSRSPTALRMARTCWLYYFSKFIELLDTIFFVLRKKNSQVTFLHVFHH 151

  Fly   145 STMFVFCWILIKWMPTGSTYVPAMINSFVHIIMYGYYALSVLGPRVQRFLWWKRYLTGLQLVQFT 209
            :.|....|..:|:...|.....|::|:.||::||.||.||.|||..|::||||:|||.||||||.
Human   152 TIMPWTWWFGVKFAAGGLGTFHALLNTAVHVVMYSYYGLSALGPAYQKYLWWKKYLTSLQLVQFV 216

  Fly   210 IIFFWASQ-MLVRGCEY--GTWITLSMAIYSLPFLFMFGKFYMQKYT 253
            |:....|| ..:..|:|  ..:..:.|: ||..||.:|..|:.:.||
Human   217 IVAIHISQFFFMEDCKYQFPVFACIIMS-YSFMFLLLFLHFWYRAYT 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Elo68alpha	NP_729666.2	ELO	23..260	CDD:279492	86/235 (37%)
ELOVL7	NP_001098028.1	ELO	30..269	CDD:307345	86/234 (37%)
ELOVL7	NP_001098028.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03207	277..281
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100254
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.720