DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir67c and Ir94d

DIOPT Version :9

Sequence 1:	NP_729609.1	Gene:	Ir67c / 317838	FlyBaseID:	FBgn0052058	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_001138099.1	Gene:	Ir94d / 7354412	FlyBaseID:	FBgn0259193	Length:	593	Species:	Drosophila melanogaster

Alignment Length:	608	Identity:	131/608 - (21%)
Similarity:	263/608 - (43%)	Gaps:	84/608 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LIFLNIILLSDRSESWSAREVIHQFNHDQQLQLNIYL---DCNDVELQIGQEVSNLFVNS-TADK 65
            |:.:.::|||...:|: ...:||..|.:.:::..:.|   |...:::.....||.|.:.. :.:.
  Fly     6 LLLVALVLLSPGGDSF-YHSLIHHLNRELKIEYVLLLGNFDTTWLDILWQLPVSVLQIKEHSRET 69

  Fly    66 MKILGRFSSHSLIIACFKDSTRNRTLNGVKELLW-GLQYL---PILFVVDSN---MDFYFQQALR 123
            ..:|...|.:.|.||...||..:     :.|:|: .|:.|   |:|.|:..:   ::...:....
  Fly    70 YSLLENPSHNVLTIAFVNDSPED-----ILEILYRNLRMLNTQPVLLVIRKSTIRVNSLLEWCWH 129

  Fly   124 HGFIHVLAL--NFMNGSL-YTYKPYPKVE-VHQIKDMQKFYKLTKLRNLQGQAVRTTVETMTPRC 184
            |..:.|:|:  :||...: |:|.|:|.:: :.:..|........:|.||.|..|...:...:||.
  Fly   130 HQLLKVVAIAQDFMESLIVYSYNPFPVLQFIERRLDNSTVIFEKRLENLHGYEVPIALGGSSPRL 194

  Fly   185 FRYRNRHGQLVYAGYMYRMVKEFISTYNG--TEEHVFGNVDTVPYKEGLAALKNGEIDMMPRIIH 247
            ..||:..|:|:::|.:...:|.|...||.  .:.:.|......|.::.:|:::||.:.:....|:
  Fly   195 IVYRDLEGKLIFSGPVGNFMKSFEQRYNCRLVQPYPFDESAISPARDLIASVQNGSVQIALGAIY 259

  Fly   248 ALEWYYFYRSHILYNIKTYIMVPWAEPLPKSLYFIQPFRGTVWITIMVSFVYASIVIWWIRYRQQ 312
            ....|..| |:.:..:...:|:|..|.:|.|..:...|....:...:|:.|..|:.: .:..|..
  Fly   260 PQVPYTGY-SYPIELMSWCLMMPVPEEVPHSQLYSMVFSPMAFGITIVAMVLISLTL-SMALRLH 322

  Fly   313 G---------------NSSLTQSFMDVLQLLFQLP-LSKIWHFNMGTHQVVSFIVLFVFGFMLTN 361
            |               ...|:|||.:||    :.| |.|           ..::|:.:.|.::|:
  Fly   323 GYRVSFSEYFLHDSCLRGVLSQSFYEVL----RAPALIK-----------AMYLVICLLGLLITS 372

  Fly   362 LYTAQLSSYLTTGLFKSQINTFDDLFREKRTLLVESFDAEVL----HNMTKEKIIQKEFESIILI 422
            .|.:..|:::|:.....|:.:::.:......:::...:.|:|    .||.|       :.||..:
  Fly   373 WYNSYFSTFVTSAPRFPQLTSYESIRHSNIKIVIWKPEYEMLLFFSENMEK-------YSSIFQL 430

  Fly   423 TSIEEVFKH-RKSLNTSYAYEAYEDRIAFELSQQRYLRVPIFKILKE--VYDQRPVFVALRHGLP 484
            ....:.|.| |.|.:|.|.|....::.:....|||....|:|.:..:  |:...|:...:.....
  Fly   431 QEDYKEFLHLRDSFDTRYGYMMPMEKWSLMKEQQRVFSSPLFSLQDDLCVFHTVPIVFPMVKNSI 495

  Fly   485 YVELFNNYLRRIFESGIWIKLQEDSFLEGIASGEISF----RKSKSREIKIFDKDFYFFAYILLG 545
            :.|.|:..:..:..:|:..:.::.||.|.|.:|::..    ...:.|.:|:.|     ...|...
  Fly   496 FKEPFDRLILDVTATGLLSRWRDMSFTEMIKAGQLGLEDRGHPKEFRAMKVGD-----LIQIWRF 555

  Fly   546 MGWC--VSTIALFLEL---WSFK 563
            :||.  ::||...|||   |..|
  Fly   556 VGWMLGLATIVFLLELICFWRHK 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir67c	NP_729609.1	Lig_chan	288..500	CDD:278489	44/234 (19%)
Ir94d	NP_001138099.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010