DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir67c and Ir94h

DIOPT Version :9

Sequence 1:	NP_729609.1	Gene:	Ir67c / 317838	FlyBaseID:	FBgn0052058	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_651148.2	Gene:	Ir94h / 42769	FlyBaseID:	FBgn0039080	Length:	559	Species:	Drosophila melanogaster

Alignment Length:	543	Identity:	120/543 - (22%)
Similarity:	216/543 - (39%)	Gaps:	120/543 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 RFSSHSLIIACFKDSTRNRTLNGVKELLWGLQYLPILF-VVDSNMDFYFQQAL----RHGFIHVL 130
            |.||:..::||...::.:..|..:.|.|...:.:.:|. |.|....|...|.|    :|..::|:
  Fly    71 RHSSNLFVMACLSSTSYDGQLQLLAESLTRYRSVRVLIEVQDKEGSFLASQILLLCQQHSMLNVV 135

  Fly   131 ALNF------MNGSLYTYKPY-------------PKVEVHQIKDMQKFYKLTKLRNLQGQAVRTT 176
             |.|      :|...|...||             ||:.::|:||            |||..:|..
  Fly   136 -LYFSRWTRTLNVFSYLAFPYFKLLKQRLSGSLRPKIFINQLKD------------LQGYKIRVQ 187

  Fly   177 VETMTPRCFRYRNRHGQLVYAGYMYRMVKEFISTYNGTEEHVF-----GNVDTVPYKEGLAALKN 236
            .:...|..|.||:|||:....|:::|:|:.|..:..|..:.::     ..|....|.  :...:|
  Fly   188 PDLSPPNSFSYRDRHGECQVGGFLWRIVENFSKSLKGDTQVLYPTWAKAKVSAAEYM--IQFTRN 250

  Fly   237 GEIDM-----MPRIIHALEWYYFYRSHILYNIKTYIMVPWAEPLPKSLYF---IQPFRGTVWITI 293
            |..|:     |....|. |.|..| |:.:|:|....|:|..:||...:.|   :.|  |:..:.|
  Fly   251 GSSDIGVTTTMITFKHE-ERYRDY-SYPMYDISWCTMLPVEKPLSVEILFSHVLSP--GSALLLI 311

  Fly   294 MVSFVYASIVIWWIRYRQQGNSSLTQSFMDVLQLLFQLPLSKIWHFNMGTHQVVSFIVLFVFGFM 358
            :...::..||               ...:..|.:.|:..|     ..|.:.         :|..:
  Fly   312 LAFILFFLIV---------------PQLIKCLGITFRGRL-----IGMASR---------IFALV 347

  Fly   359 LTNLYTAQLSSYLTTGLFKSQINTFDDL---------FREKRTLLVESFDAEVLHNMTKEKIIQK 414
            :....:|||.|.|.:....::|.:||||         .|.:...|...|.|             |
  Fly   348 MLCSSSAQLLSLLMSPPLHTRIKSFDDLLTSGLKIFGIRSELYFLDGGFRA-------------K 399

  Fly   415 EFESIILITSIEEVFKHRKSLNTSYAYEAYEDRIAFELSQQRYLRVPIFKILKEV--YDQRPVFV 477
            ...:..|..:..|::.:|...|||:||.....:.....:|||:...|:|:...::  ..:.|..:
  Fly   400 YASAFHLTENPNELYDNRNYFNTSWAYTITSVKWNVIEAQQRHFAHPVFRYSTDLCFSSETPWGL 464

  Fly   478 ALRHGLPYVELFNNYLRRIFESGIWIKLQEDSFLEGIASGEISF----RKSKSREIKIFD--KDF 536
            .:.....|.|...::..:|.::|:..:....||.|.:.:|.::.    |.:..:.::|.|  |.:
  Fly   465 LIAPESFYREPLQHFTLKINQAGLITQWMTQSFHEMVRAGRMTIKDYSRTNLMKPLRIQDLRKCW 529

  Fly   537 YFFAYILLGMGWCVSTIALFLEL 559
            ..||   :|:|  .||:...:||
  Fly   530 VIFA---VGLG--TSTVVFTIEL 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir67c	NP_729609.1	Lig_chan	288..500	CDD:278489	40/222 (18%)
Ir94h	NP_651148.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010