DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir67c and Ir67b

DIOPT Version :9

Sequence 1:	NP_729609.1	Gene:	Ir67c / 317838	FlyBaseID:	FBgn0052058	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_648393.1	Gene:	Ir67b / 39194	FlyBaseID:	FBgn0036083	Length:	574	Species:	Drosophila melanogaster

Alignment Length:	576	Identity:	180/576 - (31%)
Similarity:	315/576 - (54%)	Gaps:	43/576 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LIFLNIILLSDRSESWSAREVIHQFNHDQQLQLNIYLDCND----VELQIGQEVSNLFVNSTADK 65
            |::||.:......|.....:.:.:.|:..|.:||::|:..:    :|...|..|..|::.:..::
  Fly     3 LLYLNTLQSLSLLEGNRLVQTVQELNNIYQTELNVFLEFGNGADILESAQGTFVPTLWIKNPQNQ 67

  Fly    66 MKILGRFSSHSLIIACFKDSTRNRTLNGVKELLWGLQYLPILFVVD----SNMDFYFQQALRHGF 126
            ..:.|.|:|.:|.|...:|...:|.|..:...||...:|.:|...:    ..:...|.:....||
  Fly    68 KVMKGNFTSCTLTILYLEDEHLDRGLYYLANWLWEYHHLEVLIFFNGGSYDKLIQIFSRCFNEGF 132

  Fly   127 IHVLALNFMNGSLYTYKPYPKVEVHQIKDMQKFYKLT-KLRNLQGQAVRT-TVETMTPRCFRYRN 189
            ::||.:...:..|||:.||..:::..:|.:::||.|: |..:|.|..:.: .|....||.|.:|:
  Fly   133 VNVLVMLPGSDELYTFMPYQDLKILNLKSIKEFYSLSRKKMDLNGYNITSGLVIAGAPRWFSFRD 197

  Fly   190 RHGQLVYAGYMYRMVKEFISTYNGTEEHVFGNVDTVPYKEGLAALKNGEIDMMPRIIHALEWYYF 254
            |..:|:..|||.||:.:|.:.:||:...:  ||.||  .:||..|.|..||..|.:|..|:  .|
  Fly   198 RQNRLILTGYMLRMIVDFTNHFNGSVRLM--NVLTV--NDGLELLANRTIDFFPFLIRPLK--SF 256

  Fly   255 YRSHILYNIKTYIMVPWAEPLPKSLYFIQPFRGTVWITIMVSFVYASIVIWWIRYRQQGNSSLTQ 319
            ..|:|||.....::||.:.|||..:|.::|:....||..::..:|.|:.   :|...:|..|::.
  Fly   257 SMSNILYLENCGLIVPTSRPLPNWVYLLRPYAFDTWIAWLIMLIYCSLA---LRILSKGQISISA 318

  Fly   320 SFMDVLQLLFQLPLSKIWHFNMG----THQVVSFIVLFVFGFMLTNLYTAQLSSYLTTGLFKSQI 380
            :|:.||:|:..|..|:    :||    |.::..|::|...||:|||||.|||||....||::.||
  Fly   319 AFLKVLRLVMYLSGSR----DMGTRPTTRRLFLFVILTTSGFILTNLYVAQLSSNSAAGLYEKQI 379

  Fly   381 NTFDDLFREKRTLLVESFDAEVLHNMTKEKIIQKEFESI--ILITSIEEVFKHRKSLNTSYAYEA 443
            ||::||  :|...:....|.::   .|.||:|....:.:  |:.|...:|..:|::||||..:..
  Fly   380 NTWEDL--DKSDSIWPLIDVDI---KTMEKLIPDRTKLLKKIVPTLEADVDTYRRNLNTSCIHSG 439

  Fly   444 YEDRIAFELSQQRYLRVPIFKILKEVYDQRPVFVALRHGLPYVELFNNYLRRIFESGIWIKLQED 508
            :.|||.|.|.||::||.|||:....:..|:|:.::...|.||::|||.::|:||||||::|:::|
  Fly   440 FFDRIDFALYQQKFLRFPIFRKFPHLLYQQPLQISAAFGRPYLQLFNWFVRKIFESGIYLKMKDD 504

  Fly   509 SFLEGIASG--EISFRKSKSREIKIFDKDFYFFAYILLGM---GWCVSTIALFLEL 559
            ::..||.||  .::|| .:..|:|..|.::|   |::.|:   |..::|:...|||
  Fly   505 AYRHGIQSGLLNLAFR-DRHLEVKSNDVEYY---YLIAGLWFGGLTLATVCFLLEL 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir67c	NP_729609.1	Lig_chan	288..500	CDD:278489	76/217 (35%)
Ir67b	NP_648393.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468520
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2EU64
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840