DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir67c and Ir60e

DIOPT Version :9

Sequence 1:	NP_729609.1	Gene:	Ir67c / 317838	FlyBaseID:	FBgn0052058	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_611927.3	Gene:	Ir60e / 37917	FlyBaseID:	FBgn0035019	Length:	572	Species:	Drosophila melanogaster

Alignment Length:	598	Identity:	170/598 - (28%)
Similarity:	283/598 - (47%)	Gaps:	70/598 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFCWLIFLNIILLSDRSESWSAR-EVIHQFNHDQQLQLNIYLD---CNDVELQIGQEVSNLFVNS 61
            |..:|:...::.|...|:|.|.: :|:...|...|.:||:::|   |...|:....:...:.::|
  Fly     5 MISFLLVSVLLCLVGASDSESMQVQVLQDLNLALQTELNVFIDFECCATSEILHKLDSPRILLSS 69

  Fly    62 T---ADKMKILGRFSSHSLIIACFKDSTRNRTLNG-VKELLWGLQYLPILFVVDSNMDF----YF 118
            .   |..::|.|.|:..:|||....||..|..:.. :..||..|..|.|:|:.:....|    .:
  Fly    70 NSREARDLRIRGNFTESTLIIVSVMDSDLNPLVASLLPRLLDELHELHIVFLSNEEPGFPKQDLY 134

  Fly   119 QQALRHGFIHVLALNFMNG-SLYTYKPYPKVEVHQIKDMQKFYKLTK-LRNLQGQAVRTTVETMT 181
            ....:.||::|:   .|:| .||:|.|||.::...:.::.:::...: :||.||..||....|:.
  Fly   135 TYCFKEGFVNVI---LMSGKGLYSYLPYPSIQPISLSNVSEYFDRARIIRNFQGFPVRILRSTLA 196

  Fly   182 PRCFRYRNRHGQLVYAGYMYRMVKEFISTYNGTEEHVFGNVDTVP-YKEGLAA---LKNGEIDMM 242
            ||.|.|.|..|.||.|||::..|||....||.|.|.|  .:..:| |...||.   |...:||::
  Fly   197 PRDFEYSNEQGGLVRAGYLFTAVKELTYRYNATIESV--PIPDLPEYDVYLAVAEMLHTKKIDIV 259

  Fly   243 PRIIHALEWYYF--YRSHILYN-----IKTYIMVPWAEPLPKSLYFIQPFRGTVWITIMVSFVYA 300
                     .||  :...:.|.     |:.|.|.|.|.|:...||:.:||..|:|..::.:.:|.
  Fly   260 ---------CYFKDFSLEVAYTAPLSIIREYFMAPHARPISSYLYYSKPFGWTLWAVVISTVLYG 315

  Fly   301 SIVIWWIRYRQQGNSSLTQSFMDVLQLLFQLPLSKIWHFNMGTHQVVSFI---------VLFVFG 356
            ::::         :.:...:.:::.:.|    |..:.|.....||.:...         :|.:.|
  Fly   316 TVML---------HLAARGARVEIGKCL----LYSLSHILYNCHQKIRVAGWRDVAIHGILTIGG 367

  Fly   357 FMLTNLYTAQLSSYLTTGLFKSQINTFDDLFREKRTLLVESFDAEVLHNMTKEKIIQKE---FES 418
            |:|||:|.|.|||.||:||:..:.||.:||.|..    ..|...|...:..|.|....|   ..|
  Fly   368 FILTNVYLATLSSILTSGLYDEEYNTLEDLARAP----YPSLHDEYYRSQMKAKTFLPERLRRNS 428

  Fly   419 IILITSIEEVFKHRKSLNTSYAYEAYEDRIAFELSQQRYLRVPIFKILKEVYDQRPVFVALRHGL 483
            :.|..::.:.:  |..||.||.|..||||:...|.||..|:.|.|.::::..........:.:.|
  Fly   429 LSLNATLLKAY--RDGLNQSYIYILYEDRLELILMQQYLLKTPRFNMIRQAVGFTLESYCVSNSL 491

  Fly   484 PYVELFNNYLRRIFESGIWIKLQEDSFLEGIASGEISFRKSKSREIKIFDKDFYFFAYILLGMGW 548
            ||:.:.:.::||:.|.||.||::.|:|.|.|..|..:..:......|.||.|:||||::|..:|.
  Fly   492 PYLAMTSEFMRRLQEHGISIKMKADTFRELIHQGIYTLMRDDEPPAKAFDLDYYFFAFVLWTVGL 556

  Fly   549 CVSTIALFLELWS 561
            ..|.:..|.||.|
  Fly   557 ISSLLVFFAELVS 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir67c	NP_729609.1	Lig_chan	288..500	CDD:278489	57/223 (26%)
Ir60e	NP_611927.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468522
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940