DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir67c and Ir56c

DIOPT Version :9

Sequence 1:	NP_729609.1	Gene:	Ir67c / 317838	FlyBaseID:	FBgn0052058	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_611431.1	Gene:	Ir56c / 37251	FlyBaseID:	FBgn0034457	Length:	567	Species:	Drosophila melanogaster

Alignment Length:	578	Identity:	118/578 - (20%)
Similarity:	242/578 - (41%)	Gaps:	68/578 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 REVIHQFNHDQQL-QLNIYLDCNDVELQIGQEVSNLFVNSTADKMKILGRFSSHSLIIACFKDST 86
            :|::...:..|:| ||:.::  ..::...|:..:...||:..: |:::...:..:.:...|....
  Fly    18 QEIVWFVSPHQRLDQLDEFI--MRIDEAFGKSATQTVVNNNTE-MRMIYSSARRNHMSFVFTTGA 79

  Fly    87 RNRTLNGVKELLWGLQ-YLPILFVVDSNMD---------FYFQQALRHGFIHVLALNFMNGSLYT 141
            .:..:....::|.|.. |:.::..||...|         |.:.|...:..:|..::..:| .|:.
  Fly    80 EDPIMKVFSKVLLGRHFYVSMVIYVDKVGDMHPIYDLLTFAYNQQFFNSMVHFESMEGVN-QLFG 143

  Fly   142 YKPYPKVEVHQ----IKDMQKFYKLTKLRNLQ----GQAVRTTVETMTPRCFRYRNRHGQLVYAG 198
            ...:|.:....    :|.|.|.:|  :::|.:    |....|.:....|..|:.:..     |.|
  Fly   144 VSKFPVMSFENRTDFLKYMGKIWK--QVQNARSDVGGFGFTTPLRQDLPHLFQSQGH-----YDG 201

  Fly   199 YMYRMVKEFISTYNGTEEHVFGNVDT-----VPYKEGLAALKNGEIDMMPRIIHALEWYY----F 254
            ..||:::.|:...||:.:.:....|:     :..|:.|..::..:::.   ..||...:.    .
  Fly   202 STYRIIETFVRFINGSFKELIMPPDSLGGQVINMKDALQLIRERKMEF---CAHAYALFMSDEEL 263

  Fly   255 YRSHILYNIKTYIMVPWAEPLPKSLYFIQPFRGTVWI--------TIMVSFVYASIVIWWIRYRQ 311
            .:|:.|..::..:|||....:....|.:|||...||.        .:::..::..:...|..||
  Fly   264 EKSYPLLVVQWCLMVPLYNSVSTYFYPLQPFDWNVWFFALGALLALVLLELMWLRMFGGWSGYR- 327

  Fly   312 QGNSSLTQSFMDVLQLLFQLPLSKIWHFNMGTHQVVSFIVL---FVFGFMLTNLYTAQLSSYLTT 373
               .::..||..::.:..:..|.:        ..::.|::|   |..||.|:..||:.|.|.||.
  Fly   328 ---GAVLNSFCYIINVPIEGQLQQ--------PCLLRFLLLATVFFHGFFLSAYYTSNLGSILTV 381

  Fly   374 GLFKSQINTFDDLFREKRTLLVESFDAEVLHNMTKEKIIQKEFESIILITSIEEVFKHRKSLNTS 438
            .||.:||||.:|:...:..:::..::.|.|.|:.||  :.:||..::.........:|:.|.|:|
  Fly   382 NLFHAQINTMNDIVSAQLPVMIIDYEMEFLLNLNKE--LPQEFLELLRPVDSAVFSEHQTSFNSS 444

  Fly   439 YAYEAYEDRIAFELSQQRYLRVPIFKILKEVYDQRPVFVALRHGLPYVELFNNYLRRIFESGIWI 503
            :||...||...|...||::|:..:||:....:....:...|:...........:..||..||:..
  Fly   445 FAYFVTEDHWEFLDEQQKHLKQRLFKLSSICFGSYHLAFPLQMDSSLWRDIEYFTFRIHSSGLLN 509

  Fly   504 KLQEDSFLEGIASGEISFRKSKSREIKIFDKDFYFFAYILLGMGWCVSTIALFLELWS 561
            .....||...:.:|.:. |...::|...........|:|||.:...::.|...||..|
  Fly   510 FYARSSFGSALHAGLVQ-RMPDTQEYTSAGLQHLAIAFILLLVMSFLAGIVFVLETLS 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir67c	NP_729609.1	Lig_chan	288..500	CDD:278489	51/222 (23%)
Ir56c	NP_611431.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010