DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir67c and Ir20a

DIOPT Version :9

Sequence 1:	NP_729609.1	Gene:	Ir67c / 317838	FlyBaseID:	FBgn0052058	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_608456.1	Gene:	Ir20a / 33126	FlyBaseID:	FBgn0031181	Length:	563	Species:	Drosophila melanogaster

Alignment Length:	537	Identity:	120/537 - (22%)
Similarity:	211/537 - (39%)	Gaps:	93/537 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 RFSSHSLIIACF-KDSTRNRTLNGVKELLWGLQYLPILFVVDSNMD------FYFQQALRHGFIH 128
            :|::..|::||. .||.....|..:...|..|:.:..|.:..:..|      .|....||...:|
  Fly    74 QFNAKLLVLACLPMDSRAAIQLEILANSLSHLRTVVRLLIEVAGPDQVTLARQYLSFCLRRSMLH 138

  Fly   129 VLALNFMNGS----LYTYKPYPKVEV----HQIKDMQKFYKLTKLRNLQGQAVRTTVETMTPRCF 185
            | .|.|.:..    ||:::.:|..|:    ..:....|.: |.||.:|:|..:|...:...|..|
  Fly   139 V-ELYFRDYHHSLILYSFRAFPSFELVMRWISVGQGVKLF-LHKLDDLRGHRLRVIPDLSPPNTF 201

  Fly   186 RYRNRHGQLVYAGYMYRMVKEFISTYNGTEEHV-----FGNVDTVPYKEGLAALKNGEIDMMPRI 245
            .||:..|.....||::..:..|....|...|.|     .|:.....|....:|  .|.||:....
  Fly   202 FYRDARGDNQVTGYLWDFLATFAGRLNAGLEVVRPSWRAGSASDSSYMLEYSA--KGLIDVGLTT 264

  Fly   246 IHALEWYYFYRSHILYNIKTY----IMVPWAEPLP--KSLYFIQPFRGTVWITIMVSFVYASIVI 304
            ....:|.       |:.|..|    ::..|...||  |.|.....|...|..|:.::.:.. |::
  Fly   265 TLITKWN-------LWAIHQYTYPLLVSSWCTMLPVEKPLATPDLFGRIVCPTLAMTLLLI-ILV 321

  Fly   305 WWIRYRQQGNSSLTQSFMDVLQLLFQLPLSKIWHFNMGTHQVVSFIVLFVFGFMLTNLYTAQLSS 369
            .|:.:||             |:.|.:|..|:           .:.||..:...:|....:|||.|
  Fly   322 TWLVFRQ-------------LRCLTRLKNSR-----------PARIVPHLLTLLLLTTCSAQLLS 362

  Fly   370 YLTTGLFKSQINTFDDLFREKRTLL-----VESFDAEVLHNMTKEKIIQKEFESII-LITSIEEV 428
            .|....:..:|.:|:||.|..:.:|     ..:||.          ..:..:..:. ||....|:
  Fly   363 LLIFPPYHVRIASFEDLLRGDQKILGMRNEFYNFDG----------AFRARYAGVFYLIDDPNEL 417

  Fly   429 FKHRKSLNTSYAYEAYEDRIAFELSQQRYLRVPIFKILKEV--YDQRPVFVALRHGLPYVELFNN 491
            :..|...||::||.....:.....:|||:...|:|:..|::  :|..|..|.:.....|.|...:
  Fly   418 YDLRNHFNTTWAYTMPYIKWLVIKTQQRHFSKPLFRWSKDLCFFDFMPTSVIVAPDSIYWESIKD 482

  Fly   492 YLRRIFESGI---WIKLQEDSFLEGIASGEISFRKSKSRE----IKIFDKDFYFFAYILLGMGWC 549
            :..||.::|:   ||:   .||.:.|.:|::|.:.....|    :.|.|.:   ..:.:.|....
  Fly   483 FTFRIHQAGLMKHWIR---KSFYDMIKAGKMSIKDYSDLETLKPLNIGDLE---IVWRVCGAAIA 541

  Fly   550 VSTIALFLELWSFKYSV 566
            |::....:||..|..:|
  Fly   542 VASAIFIMELLYFYINV 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir67c	NP_729609.1	Lig_chan	288..500	CDD:278489	47/219 (21%)
Ir20a	NP_608456.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010