Protein Alignment Ir67c and Ir31a

DIOPT Version :10

• Sequence 1: NP_729609.1
• Gene: Ir67c / 317838
• FlyBaseID: FBgn0052058
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_001260346.1
• Gene: Ir31a / 318912
• FlyBaseID: FBgn0051718
• Length: 648
• Species: Drosophila melanogaster
• Alignment Length: 644
• Identity: 131/644 - (20%)
• Similarity: 231/644 - (35%)
• Gaps: 180/644 - (27%)

  Fly    39 IYLDCNDVEL---QIGQEVSNLFVNSTADKMKILGR--FSSHSLII--AC------FKDSTRNRT 90
            ::.|..::.|   :|.|.||.:.:|.:.....||.|  ::..|:::  .|      ..:::.||.
  Fly    47 LFKDFKEISLALMRINQFVSVVNLNQSYSLTSILTRENYARTSVMVNARCSGSSELLFEASENRY 111

  Fly    91 LNGVKE-LLWGL-----QYLPI-LFVVDSNMDFYFQQALRHGF----IHV------------LAL 132
            .|...: .|||:     ...|: |..|..|....:......|:    ||.            |..
  Fly   112 FNKTYQWFLWGVDLEVQSLFPLNLNYVGPNAQITYVNETADGYAYWDIHSKGRHLKSNLEINLIA 176

  Fly   133 NFMNGSLYTYKPYPKVEVHQIKDMQ---KFYKLTKLRNLQGQAV--------RTTVETMTPRCFR 186
            ..:|.:|...:     ::..::.:.   :|..||    |:|.:|        ...:|::..|..:
  Fly   177 TLINDTLNIAR-----DIFHLQSIDFRGQFNGLT----LRGASVIDKEDIISNEQIESILSRPTK 232

  Fly   187 YRNRHGQLVYAGYMYRMV----KEFISTYNGTEEHVF-GNVDTVPYKEGLAAL-KNGEIDM---- 241
               ..|...:..|.|.::    :.|..|.|......: |.:....::.||..: ...|.|:
  Fly   233 ---DAGVAAFIKYHYELLGLLRERFNFTVNFRNSRGWAGRLGNTTFRLGLLGIVMRNEADIAASG 294

  Fly   242 -MPRIIHALEWYYFYRSHILYNIKTYIMVPWAEPLP---KSLYFIQPFRGTVWITIMVSFVYASI 302
             ..||....|   |...|..:..:|..:..:...|.   ||..|:.||...||:..:::....||
  Fly   295 AFNRINRFAE---FDTIHQSWKFETAFLYRYTSDLDTHGKSGNFLSPFSDRVWLFCLLTLGAFSI 356

  Fly   303 VIWWIRYRQQGNSSLTQSFMDVLQLLFQLPLSKIWHFNMGTHQV--------------------- 346
            :  |:.:          ..:|...|..::...|:.|.|..:..:
  Fly   357 I--WVLF----------EIIDYKILRIRVNSQKLEHLNQKSSVICIKTTCIERILQTFGACCQQG 409

  Fly   347 ---------VSFIV--LFVFGFMLTNLYTAQLSSYLTTGLFKSQ---INTFDDLFREKRTLLVES 397
                     |.|:|  ||:|..::.|.||    |.:..||..|.   .:|.|::   ..:.|..|
  Fly   410 LDPNPVDRSVRFLVMTLFLFSLVMYNYYT----SSVVGGLLSSSDQGPSTVDEI---TASPLKIS 467

  Fly   398 FDAEVLHNMTKEKIIQKEFESIILITSIEEVFKHRKSLNTSYAYEAYEDRIAFELSQQRYLRVPI 462
            |:     ::...|::.:|.::..:...||:.....:|||....:...||.:.       ||:...
  Fly   468 FE-----DIGYYKVLFRESQNRSITRLIEKKLSSSRSLNELPIFSHIEDAVP-------YLKAGG 520

  Fly   463 FKILKEVYDQRPV----FVA-----LRH--GLPYVELFNNYLRR------IFESGIWIKLQEDSF 510
            |....||.|..||    |.|     ||.  ||..||:.|..|.:      ||::.: ...||..|
  Fly   521 FAFHCEVVDAYPVISEYFDANEICDLREVSGLMEVEILNWILHKNSQYTEIFKTAM-CNAQEKGF 584

  Fly   511 LEGIASGEISFRKSKSREIKIFDKDFYFFAY-----------ILLGMGWCVSTIALFLE 558
            :|.|.         :.|:||.......:..|           ::|..|:..|.:.|.||
  Fly   585 VERIL---------RRRQIKKPACQSLYTVYPVSLSGVLPGFVILICGFGASLLLLCLE 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir67c	NP_729609.1	7tm_GPCRs	<279..357	CDD:475119	19/109 (17%)
		TM helix 5	279..306	CDD:320097	7/26 (27%)
Ir31a	NP_001260346.1	Lig_chan	401..623	CDD:459656	57/250 (23%)