DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32026 and IDP2

DIOPT Version :9

Sequence 1:	NP_729420.1	Gene:	CG32026 / 317829	FlyBaseID:	FBgn0052026	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_013275.1	Gene:	IDP2 / 850871	SGDID:	S000004164	Length:	412	Species:	Saccharomyces cerevisiae

Alignment Length:	283	Identity:	68/283 - (24%)
Similarity:	114/283 - (40%)	Gaps:	64/283 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   488 YGD----VDIVTIRENTEGEYSGIEHTLVNGVVQSIKLITRNASLRVAEY--------------- 533
            :||    .|::.   ..|||..         :|...|..|.:..|:|.:|
Yeast   135 FGDQYKATDVIV---PEEGELR---------LVYKSKSGTHDVDLKVFDYPEHGGVAMMMYNTTD 187

  Fly   534 ------TFQYALAMKRK-KVTAVAESQVMRMSDGLFLRCVREMAAK-YKSKMDQAGIKYEESTMT 590
                  ...:.||::|| .:.:..::.:::..||.|......|.|: ||.|.:..||.||...:.
Yeast   188 SIEGFAKASFELAIERKLPLYSTTKNTILKKYDGKFKDVFEAMYARSYKEKFESLGIWYEHRLID 252

  Fly   591 TVCLNIVQDPKRYDMLVLPNLYGDIISDTCAGLIGGLGLTPSGNVGTNGAIFES--VHGTA---- 649
            .:...:::....| ::.:.|..||:.||..|...|.|||..|..:..:|..|||  .|||.
Yeast   253 DMVAQMLKSKGGY-IIAMKNYDGDVESDIVAQGFGSLGLMTSVLITPDGKTFESEAAHGTVTRHF 316

  Fly   650 -PDIAGKDLA-NPTALLLSSVMMLHYIGLHEHADKI-------EKAVLKTIRDDNIRTMDLG--- 702
             ....||:.: |..|.:.:....:...|..::...:       |.|.:.|:::|.|.|.||.
Yeast   317 RQHQQGKETSTNSIASIFAWTRGIIQRGKLDNTPDVVKFGQILESATVNTVQEDGIMTKDLALIL 381

  Fly   703 GKAKCS------EYTDALIKNLK 719
            ||::.|      |:.||:...||
Yeast   382 GKSERSAYVTTEEFIDAVESRLK 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32026	NP_729420.1	FGF-BP1	<281..361	CDD:284004
CG32026	NP_729420.1	Iso_dh	382..718	CDD:294303	66/280 (24%)
IDP2	NP_013275.1	nadp_idh_euk	2..409	CDD:129233	68/283 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910