DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32026 and IDH-III

DIOPT Version :9

Sequence 1:	NP_729420.1	Gene:	CG32026 / 317829	FlyBaseID:	FBgn0052026	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_195290.1	Gene:	IDH-III / 829717	AraportID:	AT4G35650	Length:	368	Species:	Arabidopsis thaliana

Alignment Length:	346	Identity:	161/346 - (46%)
Similarity:	224/346 - (64%)	Gaps:	19/346 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   380 GEPRVITLMPGDGIGPEISMAVIKILEAAKTPLIFEPVDVTPVLNSQGMTSVPEQVIESMNRTKV 444
            |.||.:||:|||||||.::.||.:::||...|:.||..:|.     ..|..|||:||||:.|.||
plant    36 GAPRTVTLIPGDGIGPLVTGAVEQVMEAMHAPVHFERYEVL-----GNMRKVPEEVIESVKRNKV 95

  Fly   445 GLKGPLMTPVGTGFRSLNLTLRQLFNLYANIRPCRSLPGVETVYGDVDIVTIRENTEGEYSGIEH 509
            .|||.|.||||.|..|||:.||:..:::|::..|.::||:.|.:.:||||.|||||||||||:||
plant    96 CLKGGLATPVGGGVSSLNMQLRKELDIFASLVNCINVPGLVTRHENVDIVVIRENTEGEYSGLEH 160

  Fly   510 TLVNGVVQSIKLITRNASLRVAEYTFQYALAMKRKKVTAVAESQVMRMSDGLFLRCVREMAAKYK 574
            .:|.|||:|:|:||:..|.|:|.|.|:||....|||||||.::.:|:::|||||...||:|..|
plant   161 EVVPGVVESLKVITKFCSERIARYAFEYAYLNNRKKVTAVHKANIMKLADGLFLESCREVAKHY- 224

  Fly   575 SKMDQAGIKYEESTMTTVCLNIVQDPKRYDMLVLPNLYGDIISDTCAGLIGGLGLTPSGNVGTNG 639
                 :||.|.|..:...|:.:|..|:::|::|.|||||::|::|.||:.||.|:.|.||||...
plant   225 -----SGITYNEIIVDNCCMQLVAKPEQFDVMVTPNLYGNLIANTAAGIAGGTGVMPGGNVGAEH 284

  Fly   640 AIFESVHGTAPDIAGKD------LANPTALLLSSVMMLHYIGLHEHADKIEKAVLKTIRDDNIRT 698
            ||||  .|.:....|.|      .|||.||||||.|||.::.....||::|.||.:.|::...||
plant   285 AIFE--QGASAGNVGNDKMVEQKKANPVALLLSSAMMLRHLRFPTFADRLETAVKQVIKEGKYRT 347

  Fly   699 MDLGGKAKCSEYTDALIKNLK 719
            .||||.....|..||:|..|:
plant   348 KDLGGDCTTQEVVDAVIAALE 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32026	NP_729420.1	FGF-BP1	<281..361	CDD:284004
CG32026	NP_729420.1	Iso_dh	382..718	CDD:294303	159/341 (47%)
IDH-III	NP_195290.1	PLN00123	8..368	CDD:215065	160/344 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D868374at2759
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820