DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32026 and idh3g

DIOPT Version :9

Sequence 1:	NP_729420.1	Gene:	CG32026 / 317829	FlyBaseID:	FBgn0052026	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_001230101.1	Gene:	idh3g / 550579	ZFINID:	ZDB-GENE-050417-435	Length:	391	Species:	Danio rerio

Alignment Length:	381	Identity:	147/381 - (38%)
Similarity:	231/381 - (60%)	Gaps:	26/381 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   353 ASKPPVKSPAGGQGQKGGAG--GKSGKASGEPRVI------------TLMPGDGIGPEISMAVIK 403
            |.||.:....|...:..|||  .:.||.:...|:|            ||:||||||||:...|.:
Zfish     8 ALKPILGRQLGNTAKVFGAGVVSQRGKPTYSGRIIPPPAKYGGRHTVTLIPGDGIGPELLNHVRE 72

  Fly   404 ILEAAKTPLIFEPVDVTPVLNSQGMTSVPEQVIESMNRTKVGLKGPLMT--PVGTGFRSLNLTLR 466
            :...:..|:.||.|.|.....|:...|   ..|.::.|..|.|||.:.|  .:....:|.|..||
Zfish    73 LFRFSCVPVDFEVVHVNSSSTSEDDIS---NAIMAIRRNGVALKGNIETNHTMPPNHKSRNNLLR 134

  Fly   467 QLFNLYANIRPCRSLPGVETVYGDVDIVTIRENTEGEYSGIEHTLVNGVVQSIKLITRNASLRVA 531
            ...:||||:..|:|||||:|.:.::||:.||||||||||.:||...:|||:.:|:||||.|||:|
Zfish   135 TSLDLYANVMHCQSLPGVQTRHKNIDIIIIRENTEGEYSSLEHESASGVVECLKIITRNNSLRIA 199

  Fly   532 EYTFQYALAMKRKKVTAVAESQVMRMSDGLFLRCVREMAAKYKSKMDQAGIKYEESTMTTVCLNI 596
            :|.|:.|....|::||||.::.:|::.|||||:|.:|:|:.|..      |::|...:....:.:
Zfish   200 DYAFKLAREKGRRRVTAVHKANIMKLGDGLFLQCCKEVASGYPD------IEFENMIVDNTTMQL 258

  Fly   597 VQDPKRYDMLVLPNLYGDIISDTCAGLIGGLGLTPSGNVGTNGAIFE-SVHGTAPDIAGKDLANP 660
            |..|.::|::|:|||||:::|:.||||:||.||.|..|.|.:.|:|| :...|...||.:::|||
Zfish   259 VSKPYQFDVMVMPNLYGNVVSNVCAGLVGGPGLVPGANYGRDYAVFETATRNTGKSIANRNIANP 323

  Fly   661 TALLLSSVMMLHYIGLHEHADKIEKAVLKTIRDDNIRTMDLGGKAKCSEYTDALIK 716
            ||:||:|.:||.::.||::|:.|..|:|.|:.:..:.|:|:||:...||...::::
Zfish   324 TAMLLASCLMLDHLKLHDYANMIRSAILTTMNETRLHTVDIGGQGTTSEVVQSIMR 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32026	NP_729420.1	FGF-BP1	<281..361	CDD:284004	3/7 (43%)
CG32026	NP_729420.1	Iso_dh	382..718	CDD:294303	138/350 (39%)
idh3g	NP_001230101.1	mito_nad_idh	49..381	CDD:272942	136/340 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D325037at33208
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X402
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820