DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32026 and IDH3G

DIOPT Version :9

Sequence 1:	NP_729420.1	Gene:	CG32026 / 317829	FlyBaseID:	FBgn0052026	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_004126.1	Gene:	IDH3G / 3421	HGNCID:	5386	Length:	393	Species:	Homo sapiens

Alignment Length:	348	Identity:	146/348 - (41%)
Similarity:	220/348 - (63%)	Gaps:	14/348 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   375 SGKASGEPRVITLMPGDGIGPEISMAVIKILEAAKTPLIFEPVDVTPVLNSQGMTSVPEQVIESM 439
            |.|..|. ..:|::||||||||:.:.|..:...|..|:.||.|.|:...:.:.:    ...|.::
Human    48 SAKYGGR-HTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDI----RNAIMAI 107

  Fly   440 NRTKVGLKGPLMT--PVGTGFRSLNLTLRQLFNLYANIRPCRSLPGVETVYGDVDIVTIRENTEG 502
            .|.:|.|||.:.|  .:....:|.|..||...:||||:..|:|||||.|.:.|:||:.:||||||
Human   108 RRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEG 172

  Fly   503 EYSGIEHTLVNGVVQSIKLITRNASLRVAEYTFQYALAMKRKKVTAVAESQVMRMSDGLFLRCVR 567
            |||.:||..|.|||:|:|:||:..|||:|||.|:.|....|||||||.::.:|::.|||||:|.|
Human   173 EYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCR 237

  Fly   568 EMAAKYKSKMDQAGIKYEESTMTTVCLNIVQDPKRYDMLVLPNLYGDIISDTCAGLIGGLGLTPS 632
            |:||:|..      |.:|...:....:.:|..|:::|::|:|||||:|:::.||||:||.||...
Human   238 EVAARYPQ------ITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAG 296

  Fly   633 GNVGTNGAIFE-SVHGTAPDIAGKDLANPTALLLSSVMMLHYIGLHEHADKIEKAVLKTIRDDNI 696
            .|.|...|:|| :...|...||.|::|||||.||:|.|||.::.||.:|..|.||||.::.::|:
Human   297 ANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENM 361

  Fly   697 RTMDLGGKAKCSEYTDALIKNLK 719
            .|.|:||:...||....:|::::
Human   362 HTPDIGGQGTTSEAIQDVIRHIR 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32026	NP_729420.1	FGF-BP1	<281..361	CDD:284004
CG32026	NP_729420.1	Iso_dh	382..718	CDD:294303	143/338 (42%)
IDH3G	NP_004126.1	mito_nad_idh	52..383	CDD:272942	144/341 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D325037at33208
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X402
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820