DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32026 and idh1

DIOPT Version :9

Sequence 1:	NP_729420.1	Gene:	CG32026 / 317829	FlyBaseID:	FBgn0052026	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_594397.1	Gene:	idh1 / 2541894	PomBaseID:	SPAC11G7.03	Length:	356	Species:	Schizosaccharomyces pombe

Alignment Length:	351	Identity:	136/351 - (38%)
Similarity:	210/351 - (59%)	Gaps:	17/351 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   372 GGKSGKASGEPRVITLMPGDGIGPEISMAVIKILEAAKTPLIFEPVDVTPV-LNSQGMTSVPEQV 435
            |||        ..:||:||||||.|.|.||.:|.:.|..|:.||.:|||.: .|::.......:.
pombe    18 GGK--------YTVTLIPGDGIGRETSNAVTEIFKTANVPIEFEEIDVTGMEKNNKSSGDALHEA 74

  Fly   436 IESMNRTKVGLKGPLMTPVGT-GFRSLNLTLRQLFNLYANIRPCRSLPGVETVYGDVDIVTIREN 499
            |:|:.|.||||||.|.||... |..|.|:.||:..::||::...:::||.:|.:.:||...||||
pombe    75 IQSLKRNKVGLKGILFTPFEKGGHTSFNVALRKELDIYASLVLIKNIPGFKTRHDNVDFAIIREN 139

  Fly   500 TEGEYSGIEHTLVNGVVQSIKLITRNASLRVAEYTFQYALAMKRKKVTAVAESQVMRMSDGLFLR 564
            |||||||:||..|.|||:|:|:||...|.|:|::.|.:||...||.||.:.::.:|:::||||.|
pombe   140 TEGEYSGLEHQSVPGVVESLKIITEYKSKRIAQFAFDFALQNGRKSVTCIHKANIMKLADGLFRR 204

  Fly   565 CVREMAAKYKSKMDQAGIKYEESTMTTVCLNIVQDPKRYDMLVLPNLYGDIISDTCAGLIGGLGL 629
            ...::|..|.:      |..::..:....:..|..|:::|:||:|||||.|:|:..:.|:||.|:
pombe   205 TFYDVANGYDA------ITPKDLIVDNASMQAVSRPQQFDVLVMPNLYGSILSNIGSALVGGPGV 263

  Fly   630 TPSGNVGTNGAIFE-SVHGTAPDIAGKDLANPTALLLSSVMMLHYIGLHEHADKIEKAVLKTIRD 693
            .|..|.|.:.|:|| ........|.|:..|||||.:||:.:||.::||.::||.|..|....|.:
pombe   264 IPGANFGRDYALFEPGCRHVGLSITGRGEANPTAAILSACLMLRHLGLKDYADLINAATYSVIEE 328

  Fly   694 DNIRTMDLGGKAKCSEYTDALIKNLK 719
            ....|.||||.|...::|.|:::.::
pombe   329 GKTLTKDLGGSASTGDFTHAILERME 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32026	NP_729420.1	FGF-BP1	<281..361	CDD:284004
CG32026	NP_729420.1	Iso_dh	382..718	CDD:294303	133/338 (39%)
idh1	NP_594397.1	mito_nad_idh	18..353	CDD:272942	136/348 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810