DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32026 and idh-2

DIOPT Version :9

Sequence 1:	NP_729420.1	Gene:	CG32026 / 317829	FlyBaseID:	FBgn0052026	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	NP_001370015.1	Gene:	idh-2 / 181311	WormBaseID:	WBGene00007942	Length:	435	Species:	Caenorhabditis elegans

Alignment Length:	351	Identity:	74/351 - (21%)
Similarity:	128/351 - (36%)	Gaps:	81/351 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   424 NSQGMTSVPEQVIESMNRTKVGLKGPLMTPVGTGFRSLNL---------TLRQLFNLYANIRP-- 477
            |.|........::|.    .||:|...:||.....:..||         |:|.:........|
Worm    76 NDQVTIDAAHAILEH----SVGIKCATITPDEARIKEFNLKKMWLSPNGTIRNILGGTVFREPIL 136

  Fly   478 CRSLPGVETVYGDVDIVTIRENTEG-EYSGIEHTLVNGV--------------VQSIKLITRNAS 527
            |:::|  ..|.|....:||..:..| :|...:..:.:|.              |.::....::..
Worm   137 CKNIP--RLVPGWTQPITIGRHAFGDQYKCTDLVIPSGSTLQLLVNKPDGSKDVHNVYDFKKSGG 199

  Fly   528 LRVAEYT------------FQYALAMKRKKVTAVAESQVMRMSDGLFLRCVREM-AAKYKSKMDQ 579
            :.:|.|.            ||||| ||:..:....::.:::..||.|....::: ..||::....
Worm   200 VGLAMYNTDESIKGFAHSCFQYAL-MKQWPLYLSTKNTILKKYDGRFKDIFQDIYEKKYEADFKN 263

  Fly   580 AGIKYEESTMTTVCLNIVQDP-------KRYDMLVLPNLYGDIISDTCAGLIGGLGLTPSGNVGT 637
            ..|.||...:.......::..       |.||        ||:.||..|...|.|||..|..:..
Worm   264 NKIWYEHRLIDDQVAQALKSSGGFVWACKNYD--------GDVQSDIVAQGYGSLGLMSSVLMCP 320

  Fly   638 NGAIF--ESVHGTAP------DIAGKDLANPTALLLSSVMMLHYIGLHEHAD-------KIEKAV 687
            :|...  |:.|||..      ........||.|.:.:....||:.|:.::.:       .:|||.
Worm   321 DGKTIEAEAAHGTVTRHYREHQKGNSTSTNPIASIFAWTRGLHHRGVLDNNEALKTFSLTLEKAC 385

  Fly   688 LKTIRDDNIRTMDLG----GKAKCSE 709
            :.|:.:..: |.||.    |..|.:|
Worm   386 IDTVEEGKM-TKDLSICIHGTKKGTE 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32026	NP_729420.1	FGF-BP1	<281..361	CDD:284004
CG32026	NP_729420.1	Iso_dh	382..718	CDD:294303	74/351 (21%)
idh-2	NP_001370015.1	PTZ00435	25..434	CDD:240417	74/351 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910