DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32026 and Idh3a

DIOPT Version :9

Sequence 1:	NP_729420.1	Gene:	CG32026 / 317829	FlyBaseID:	FBgn0052026	Length:	719	Species:	Drosophila melanogaster
Sequence 2:	XP_038936589.1	Gene:	Idh3a / 114096	RGDID:	70889	Length:	374	Species:	Rattus norvegicus

Alignment Length:	338	Identity:	202/338 - (59%)
Similarity:	258/338 - (76%)	Gaps:	7/338 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   383 RVITLMPGDGIGPEISMAVIKILEAAKTPLIFEPVDVTPVLNSQGMTSVPEQVIESMNRTKVGLK 447
            :.:||:||||||||||.:|:||.:|||.|:.:|..:||.:....|...:|.:..|||::.|:|||
  Rat    40 QTVTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPPEAKESMDKNKMGLK 104

  Fly   448 GPLMTPVGTGFRSLNLTLRQLFNLYANIRPCRSLPGVETVYGDVDIVTIRENTEGEYSGIEHTLV 512
            |||.||:..|..|:||.||:.|:||||:|||.|:.|.:|.|.||:|||||||||||||||||.:|
  Rat   105 GPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIV 169

  Fly   513 NGVVQSIKLITRNASLRVAEYTFQYALAMKRKKVTAVAESQVMRMSDGLFLRCVREMAAKYKSKM 577
            :||||||||||..||.|:||:.|:||....|..||||.::.:|||||||||:..||:|...|.
  Rat   170 DGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAENCKD-- 232

  Fly   578 DQAGIKYEESTMTTVCLNIVQDPKRYDMLVLPNLYGDIISDTCAGLIGGLGLTPSGNVGTNG-AI 641
                ||:.|..:.|||||:||||.::|:||:|||||||:||.|||||||||:|||||:|.|| ||
  Rat   233 ----IKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI 293

  Fly   642 FESVHGTAPDIAGKDLANPTALLLSSVMMLHYIGLHEHADKIEKAVLKTIRDDNIRTMDLGGKAK 706
            |||||||||||||||:|||||||||:||||.::||.:||.|||.|...||:|....|.||||.:|
  Rat   294 FESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAAKIEAACFATIKDGKSLTKDLGGNSK 358

  Fly   707 CSEYTDALIKNLK 719
            ||::|:.:.:.:|
  Rat   359 CSDFTEEICRRVK 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32026	NP_729420.1	FGF-BP1	<281..361	CDD:284004
CG32026	NP_729420.1	Iso_dh	382..718	CDD:294303	201/335 (60%)
Idh3a	XP_038936589.1	mito_nad_idh	38..370	CDD:272942	201/335 (60%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353521
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D325037at33208
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100541
Panther	1	1.100	-	-	O	PTHR11835
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X402
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.710