Protein Alignment Zyx and LIMS3

DIOPT Version :9

• Sequence 1: NP_652015.1
• Gene: Zyx / 317824
• FlyBaseID: FBgn0011642
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001381830.1
• Gene: LIMS3 / 96626
• HGNCID: 30047
• Length: 398
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 73/318 - (22%)
• Similarity: 122/318 - (38%)
• Gaps: 81/318 - (25%)

  Fly   302 RPCVA---DTLPRESYNLHNSYVNDNNPNISHEYNISNSIEANQTLY-IHGNART-----TFYDV 357
            |||:.   :.:||.:.            |..||.|.:....|...|. .|.:.:.     .||
Human     8 RPCIIPENEEIPRAAL------------NTVHEANGTEDERAVSKLQRRHSDVKVYKEFCDFY-- 58

  Fly   358 NSIHRNDKEGLKNYISIPTEPVQELENYGRCVKCNSRVLGESSGCTAMDQIYHIFCFTCTDCQIN 422
                  .|..:.|.::..|           |.:|........:...:..::||..||.|..|...
Human    59 ------AKFNMANALASAT-----------CERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQ 106

  Fly   423 LQGKPFYALDGKPYCEYDYLQTLEK-CSVCMEPILERILRATGKPYHPQCFTCVVCGKSLDGLLF 486
            .....||..:|:.|||:|:...... |..|.|.|:.|:::|....:||:||.|.:|.:.|..:.|
Human   107 FPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGF 171

  Fly   487 TVDATNQNYCITDFHKKFAPR------CCVC-----KQPIM--PDPGQEETIRVVALDRSFHLEC 538
            ..:| .::.| ...|.:...|      |..|     :||::  .||              :|.:.
Human   172 VKNA-GRHLC-RPCHNREKARGLGKYICQKCHAIIDEQPLIFKNDP--------------YHPDH 220

  Fly   539 YKCEDCGLLLSSEA-EGRG---CYPLDDHV---LCKSC----NAKRVQALTNRMTSEH 585
            :.|.:||..|:::| |.:|   |.|..|.:   :|.:|    ..:.|.|:..:...||
Human   221 FNCANCGKDLTADAQELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEH 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	14/52 (27%)
		LIM2_LPP	448..507	CDD:188740	17/58 (29%)
		LIM3_LPP	508..575	CDD:188821	19/84 (23%)
LIMS3	NP_001381830.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900