Protein Alignment Zyx and FHL5

DIOPT Version :9

• Sequence 1: NP_652015.1
• Gene: Zyx / 317824
• FlyBaseID: FBgn0011642
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001164278.1
• Gene: FHL5 / 9457
• HGNCID: 17371
• Length: 284
• Species: Homo sapiens
• Alignment Length: 226
• Identity: 63/226 - (27%)
• Similarity: 94/226 - (41%)
• Gaps: 26/226 - (11%)

  Fly   369 KNYISIPTEPV------QELENYGRCVKCNSRVLGESSGCTAMDQIYHIFCFTCTDCQINLQGKP 427
            |.|:.....|.      :...||  |.:|...:..:|......|:.:|..||.||.|..:|..||
Human    18 KKYVLKDDSPYCVTCYDRVFSNY--CEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKP 80

  Fly   428 FYALDGKPYCEYDYL-QTLEKCSVCMEPIL--ERILRATGKPYHPQCFTCVVCGKSLDGLLFTVD 489
            |.|.|.:..|...|. :...||..|...|:  .|.:...|..:|..||.|..|.:.: |....:.
Human    81 FAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPI-GTKPLIS 144

  Fly   490 ATNQNYCITDFHKKFAPRCCVCKQPIMPDPGQEETIRVVALDRSFHLECYKCEDCGL-LLSSEAE 553
            ..:.|||:..|.|:||..|..||: ::...|      :...|:.:|.||:.|..|.. |...:..
Human   145 KESGNYCVPCFEKEFAHYCNFCKK-VITSGG------ITFCDQLWHKECFLCSGCRKDLCEEQFM 202

  Fly   554 GRGCYP--LD--DHVLCKSCNA--KRVQALT 578
            .|..||  :|  :|:....|.|  |.:..||
Human   203 SRDDYPFCVDCYNHLYANKCVACSKPISGLT 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	17/52 (33%)
		LIM2_LPP	448..507	CDD:188740	18/60 (30%)
		LIM3_LPP	508..575	CDD:188821	19/73 (26%)
FHL5	NP_001164278.1	LIM	<5..34	CDD:351770	3/15 (20%)
		LIM1_FHL	37..95	CDD:188729	19/59 (32%)
		LIM2_FHL5	102..155	CDD:188812	14/53 (26%)
		LIM3_FHL	163..214	CDD:188732	15/57 (26%)
		LIM4_FHL	222..277	CDD:188733	5/12 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810