DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Zyx and PDLIM4

DIOPT Version :9

Sequence 1:NP_652015.1 Gene:Zyx / 317824 FlyBaseID:FBgn0011642 Length:585 Species:Drosophila melanogaster
Sequence 2:NP_003678.2 Gene:PDLIM4 / 8572 HGNCID:16501 Length:330 Species:Homo sapiens


Alignment Length:61 Identity:21/61 - (34%)
Similarity:36/61 - (59%) Gaps:2/61 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly   378 PVQELENYGRCVKCNSRVLGESSGCTAMDQIYHIFCFTCTDCQINLQGKPFYALDGKPYCE 438
            |:..|:....|.:|...::|  :...|.|::||..||.|:||.:||:.:.::.||.:.|||
Human   245 PLSGLQGLPECTRCGHGIVG--TIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERLYCE 303

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZyxNP_652015.1 LIM1_LPP 388..441 CDD:188737 19/51 (37%)
LIM2_LPP 448..507 CDD:188740
LIM3_LPP 508..575 CDD:188821
PDLIM4NP_003678.2 PDZ_signaling 2..80 CDD:238492
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 104..180
DUF4749 148..220 CDD:406377
LIM_RIL 255..307 CDD:188835 19/51 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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