DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Zyx and LRG1

DIOPT Version :9

Sequence 1:	NP_652015.1	Gene:	Zyx / 317824	FlyBaseID:	FBgn0011642	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_010041.2	Gene:	LRG1 / 851358	SGDID:	S000002399	Length:	1017	Species:	Saccharomyces cerevisiae

Alignment Length:	166	Identity:	54/166 - (32%)
Similarity:	72/166 - (43%)	Gaps:	22/166 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   388 CVKCNSRVLGES----SGCTAMDQIYHIFCFTCTDCQINLQGKPF-YALDGKP----YCEYDYLQ 443
            |.:||..|:.:|    :...|:.:.||..||||.|||..|:.|.| |.:|...    .|:|||.:
Yeast    28 CARCNKLVIPDSQRTKTTLKALGKYYHESCFTCQDCQKPLKPKYFPYQVDKTSESILLCQYDYFR 92

  Fly   444 TLE-KCSVCMEPILERILRATGKPYHPQCFTCVVCGKSLDGLLFTVDATNQNYCITDFHKKFAPR 507
            ... .|.||..|:......|.|..|..:.|:|.:|.... |:.......||.||...|.|.|:.|
Yeast    93 RHNLLCHVCDTPLRGLYYTAFGYRYDEEHFSCTICATPC-GVKKCFMYGNQLYCKYHFLKYFSKR 156

  Fly   508 CCVCKQPIMPD----PGQEETIRVVALDRSFHLECY 539
            |..|:.||...    |..||.       ..:|.|||
Yeast   157 CKGCEFPISDQYIEFPKGEEI-------HCWHPECY 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	22/61 (36%)
		LIM2_LPP	448..507	CDD:188740	18/58 (31%)
		LIM3_LPP	508..575	CDD:188821	11/36 (31%)
LRG1	NP_010041.2	LIM1_Lrg1p_like	28..90	CDD:188777	22/61 (36%)
		LIM	98..149	CDD:259829	15/51 (29%)
		LIM3_Lrg1p_like	419..475	CDD:188779
		RhoGAP_fLRG1	728..959	CDD:239862
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000