Protein Alignment Zyx and lpp

DIOPT Version :9

• Sequence 1: NP_652015.1
• Gene: Zyx / 317824
• FlyBaseID: FBgn0011642
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_957492.1
• Gene: lpp / 573024
• ZFINID: ZDB-GENE-040426-918
• Length: 556
• Species: Danio rerio
• Alignment Length: 644
• Identity: 212/644 - (32%)
• Similarity: 283/644 - (43%)
• Gaps: 176/644 - (27%)

  Fly    10 ELSLPKGDTGSPLVCIGHGKVAKLVAKI--------SNNQNASVKRRLDIPPKPP--IKYNEMPQ 64
            |.|||.|.|.   :.|...:..|..|.:        ...|........|.||.||  :..:.:|.
Zfish    19 ETSLPMGTTS---ISISQQQAPKKFAPVVAPKPKFNPYKQPGDATHEGDYPPPPPPVVDPSGLPS 80

  Fly    65 VPSSRQVLCSREPLYSQP-----------LIGVEKTMRGHMPFRKYLSSEFGVADTQINRKTTLD 118
             |||          :..|           :.|.|||:...   |..|.:|             :|
Zfish    81 -PSS----------FPPPPPMDETSLGFQIKGPEKTLEER---RSSLDAE-------------ID 118

  Fly   119 NPAILEQQLEALAYHKLQMEKKGLLGVQAKPTQPLNSFTKPLSKTLSKSLIYSNLGSVRKEIETL 183
            :...:...||:.:.:|.:.::..........|.|:..:.                   |..|.|.
Zfish   119 SLTSILADLESSSPYKPRTQQNSASPAATGSTAPVTGYR-------------------RMVIPTQ 164

  Fly   184 ELLTDETKISASTYSNVNETAMDSSHSSTQKMLSVCTNFISDNEKDELPPPPSPESAVSSSYSEL 248
            ..||...|.:....:..|.|...||                 :.:.:..|.|.|   |.:||:..
Zfish   165 PPLTATKKSTPKPQAPQNVTPPASS-----------------SPRPQYQPAPQP---VPASYTTA 209

  Fly   249 RHATLEFNKPIDYLQNNQTTNPLQIYANQYA-MQHDATGKSSSTY--------DSIYEPINPRPC 304
                   :.|      :|.|..:|:.|.|.| .|....|.....|        :..|.|..|..|
Zfish   210 -------STP------SQPTFNVQVRAAQPAPQQQPVRGPGQVQYMPAQPRAPEFAYGPPQPGFC 261

  Fly   305 VADTLPRESYNLHNSYVNDNNPNISHEYNISNSIEANQTLYIHGNARTTFYDVNSIHRNDKEGL- 368
            .|   |...|       .|.:...:..|...|:..|..:   |..|.|           ..:|.
Zfish   262 PA---PSGGY-------QDQHYGGAPGYGGQNTWRAEPS---HHPAPT-----------PSQGYQ 302

  Fly   369 -----KNYISIPT----------------EPVQEL-----------------ENYGRCVKCNSRV 395
                 |.||:.|.                .|.:||                 |.:|||..|...|
Zfish   303 PAPPKKTYITDPPASLAPFAGGSSAPHKGRPEEELDRLTKKMLYDMDNPPSEEYFGRCSSCGENV 367

  Fly   396 LGESSGCTAMDQIYHIFCFTCTDCQINLQGKPFYALDGKPYCEYDYLQTLEKCSVCMEPILERIL 460
            :||.:|||||||::|:.||.|..|...|:||||||::.|.|||..|:.|||.|::|.:||:||||
Zfish   368 VGEGTGCTAMDQVFHVDCFICMTCGSKLRGKPFYAVEKKAYCEPCYINTLETCNICYKPIMERIL 432

  Fly   461 RATGKPYHPQCFTCVVCGKSLDGLLFTVDATNQNYCITDFHKKFAPRCCVCKQPIMPDPGQEETI 525
            |||||.|||||||||||.:||||:.|||||:|..:||.||||||||||.||.:||||.||||||:
Zfish   433 RATGKAYHPQCFTCVVCHRSLDGIPFTVDASNHIHCIEDFHKKFAPRCSVCNEPIMPAPGQEETV 497

  Fly   526 RVVALDRSFHLECYKCEDCGLLLSSEAEGRGCYPLDDHVLCKSCNAKRVQALTNRMTSE 584
            |:|||||.||::||:|||||.|| ||.:.:||||||.|||||:||..|:||||.:.|::
Zfish   498 RIVALDRDFHVQCYRCEDCGCLL-SEGDNQGCYPLDGHVLCKNCNTSRIQALTAKATTD 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	28/52 (54%)
		LIM2_LPP	448..507	CDD:188740	43/58 (74%)
		LIM3_LPP	508..575	CDD:188821	46/66 (70%)
lpp	NP_957492.1	DUF2413	123..>201	CDD:287302	17/113 (15%)
		LIM1_TRIP6	360..413	CDD:188736	28/52 (54%)
		LIM	420..479	CDD:295319	43/58 (74%)
		LIM3_TRIP6	480..545	CDD:188820	45/65 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I6993
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001663
OrthoInspector	1	1.000	-	-		otm25637
orthoMCL	1	0.900	-	-		OOG6_108119
Panther	1	1.100	-	-	LDO	PTHR24207
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3402
SonicParanoid	1	1.000	-	-		X2600
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.800