DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zyx and pxnb

DIOPT Version :9

Sequence 1:	NP_652015.1	Gene:	Zyx / 317824	FlyBaseID:	FBgn0011642	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_021334029.1	Gene:	pxnb / 565130	ZFINID:	ZDB-GENE-130530-697	Length:	1197	Species:	Danio rerio

Alignment Length:	223	Identity:	61/223 - (27%)
Similarity:	97/223 - (43%)	Gaps:	43/223 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   386 GRCVKCNSRVLGESSGCTAMDQIYHIFCFTCTDCQINLQGKPFYALDGKPYCEYDYLQTLE-KCS 449
            |.|..|:..::|:.  .|||.:.:|...|.||.||..:..:.|:..:|:||||.||..... :|.
Zfish   962 GVCGACSKPIVGQV--VTAMGRTWHPEHFVCTHCQEEIGSRNFFEREGQPYCERDYHHLFSPRCY 1024

  Fly   450 VCMEPILERILRATGKPYHPQCFTCVVCG--------KSLDGLLFTVDATNQNYCITDFHKKFAP 506
            .|..|||::::.|..:.:||:.|.|..||        ...||         :.||..|:...|||
Zfish  1025 YCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDG---------KAYCRKDYFDLFAP 1080

  Fly   507 RCCVCKQPIMPDPGQEETIRVVALDRSFHLECYKCEDC------GLLLSSEAEGRGCYPLDDHV- 564
            :|..|.:.|:.:       .:.||...:|.||:.|.:|      |...  |.:|:....:..|.
Zfish  1081 KCGGCARAILEN-------YISALSSLWHPECFVCRECFTPFVNGSFF--EHDGQPYCEVHYHAR 1136

  Fly   565 ---LCKSC----NAKRVQALTNRMTSEH 585
               ||..|    ..:.:.|:..:...||
Zfish  1137 RGSLCSGCQKPITGRCITAMGKKFHPEH 1164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	18/52 (35%)
		LIM2_LPP	448..507	CDD:188740	19/66 (29%)
		LIM3_LPP	508..575	CDD:188821	17/80 (21%)
pxnb	XP_021334029.1	Paxillin	96..272	CDD:308898
		Atrophin-1	<178..684	CDD:331285
		LIM1_Paxillin_like	964..1016	CDD:259830	19/53 (36%)
		LIM2_Paxillin_like	1023..1074	CDD:188723	16/59 (27%)
		LIM3_Paxillin_like	1082..1134	CDD:188724	13/60 (22%)
		LIM4_Paxillin	1141..1192	CDD:188795	5/24 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910