DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Zyx and limd1a

DIOPT Version :9

Sequence 1:	NP_652015.1	Gene:	Zyx / 317824	FlyBaseID:	FBgn0011642	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_021322480.1	Gene:	limd1a / 562793	ZFINID:	ZDB-GENE-070712-1	Length:	187	Species:	Danio rerio

Alignment Length:	182	Identity:	92/182 - (50%)
Similarity:	124/182 - (68%)	Gaps:	8/182 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   405 MDQIYHIFCFTCTDCQINLQGKPFYALDGKPYCEYDYL-----QTLEKCSVCMEPILERILRATG 464
            |..:||..||||:.|...|:||.||.:.||.:||.|:|     |:.:|||||...|::.||:|.|
Zfish     1 MGSLYHDSCFTCSACSRKLRGKAFYFVCGKVFCEEDFLYSGFQQSADKCSVCGHLIMDMILQALG 65

  Fly   465 KPYHPQCFTCVVCGKSLDGLLFTVDATNQNYCITDFHKKFAPRCCVCKQPIMPDPGQEETIRVVA 529
            |.|||.||.|.:|.:||||:.||||..|:.||:.|:|:..||:|..|.|||:|..|.:||||||:
Zfish    66 KSYHPGCFRCAICNESLDGVPFTVDTENKIYCVKDYHRVLAPKCAACNQPILPSEGSDETIRVVS 130

  Fly   530 LDRSFHLECYKCEDCGLLLSSEAEGRGCYPLDDHVLCKSCNAKRV--QALTN 579
            :||.:|:|||.||||.:.|:.| ||..|||||.|:||.:|:.|.:  |:..|
Zfish   131 MDRDYHVECYHCEDCQMELNDE-EGHRCYPLDGHLLCHACHLKHIDPQSTAN 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	17/35 (49%)
		LIM2_LPP	448..507	CDD:188740	31/58 (53%)
		LIM3_LPP	508..575	CDD:188821	37/68 (54%)
limd1a	XP_021322480.1	LIM	<1..37	CDD:295319	17/35 (49%)
		LIM2_Ajuba_like	49..101	CDD:188741	28/51 (55%)
		LIM3_Ajuba_like	109..170	CDD:188822	35/61 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910