DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Zyx and lhx8

DIOPT Version :9

Sequence 1:	NP_652015.1	Gene:	Zyx / 317824	FlyBaseID:	FBgn0011642	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_012816489.1	Gene:	lhx8 / 548653	XenbaseID:	XB-GENE-494997	Length:	385	Species:	Xenopus tropicalis

Alignment Length:	142	Identity:	35/142 - (24%)
Similarity:	58/142 - (40%)	Gaps:	24/142 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   373 SIPTEPVQELE---------NYGR--CVKCNSRVLGESSGCTAMDQIYHIFCFTCTDCQINL-QG 425
            |:|..||....         |.|:  |..|...:: :.......|..:|:.|.:|:.|:.:| :.
Frog    78 SVPLSPVSSSSPHSMPAAGLNQGKSVCSNCGLEIV-DKYLLKVNDLCWHVRCLSCSVCRTSLGRH 141

  Fly   426 KPFYALDGKPYCEYDYLQTL-EKCSVCMEPI--LERILRATGKPYHPQCFTCVVCGKSLDGLLFT 487
            ...|..|...||:.||.:.. .:||.|...|  .:.:.||.|..||..||.|..|.:.|
Frog   142 TSCYIKDKDIYCKLDYFRRYGTRCSRCGRHIHATDWVRRAKGNVYHLACFACYSCKRQL------ 200

  Fly   488 VDATNQNYCITD 499
              :|.:.:.:.:
Frog   201 --STGEEFALVE 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	12/53 (23%)
		LIM2_LPP	448..507	CDD:188740	15/54 (28%)
		LIM3_LPP	508..575	CDD:188821
lhx8	XP_012816489.1	LIM1_Lhx7_Lhx8	103..158	CDD:188767	13/55 (24%)
		LIM2_Lhx7_Lhx8	165..219	CDD:188769	15/54 (28%)
		Homeobox	258..311	CDD:365835
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910