DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zyx and lmcd1

DIOPT Version :9

Sequence 1:	NP_652015.1	Gene:	Zyx / 317824	FlyBaseID:	FBgn0011642	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_957364.2	Gene:	lmcd1 / 394045	ZFINID:	ZDB-GENE-040426-1067	Length:	342	Species:	Danio rerio

Alignment Length:	313	Identity:	73/313 - (23%)
Similarity:	116/313 - (37%)	Gaps:	80/313 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 FISDNEKDELPPPPSPESAVSSSYSELRHATLEFNKPIDYLQNNQ-TTNPLQIYANQYAMQHDAT 285
            |||:|| |:|   ........|.|:.|.......:....|.:|.. .|||:       ..:.|.|
Zfish    45 FISNNE-DDL---KVGRLLADSRYTHLTAKVKGGDGTRVYKRNRMIVTNPV-------VSRKDPT 98

  Fly   286 GKSSSTYD-----------SIYEPINP---RPCVADT---LPRESYNLHNSYVNDNNPNISHEYN 333
             .::.|||           .:|..:.|   || ||.|   |.|...........|::|...|..:
Zfish    99 -FNTVTYDWAPTGLTQKLAMLYMSLLPEERRP-VAGTEGSLYRHKQLTRQLPAYDHDPAYCHSLS 161

  Fly   334 ------ISNSIEANQ-------TLYIHGNARTTFYDVNSIHRNDKEGLKNYISIPTEPVQELENY 385
                  ::..:::.:       .:.:.|...||       .||:|...:.    |..|:.|....
Zfish   162 EAELKVMAQFVKSYKEESLGVGEVALPGEKSTT-------KRNEKISQEQ----PDPPLTEQTPD 215

  Fly   386 GRCVKCNSRVLGES----SGC---TAMDQ------------IYHIFCFTCTDCQINLQGKPFYAL 431
            |   ...|.|..|:    |||   .|||:            ::|..||.|.:|...|....::..
Zfish   216 G---AIESPVSNETEYYCSGCGQLAAMDEPVVYADRAGYERLWHPACFVCGECGEALVDLIYFWK 277

  Fly   432 DGKPYCEYDYLQTLE-KCSVCMEPILERIL--RATGKPYHPQCFTCVVCGKSL 481
            :|...|...|.|::. :|..|.|.|...:|  .|:|..:|.:.|.|.:||:.:
Zfish   278 EGALLCGRHYCQSIRPRCLGCDELIFSDMLLQEASGHVWHKEHFCCWLCGQDI 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	17/71 (24%)
		LIM2_LPP	448..507	CDD:188740	12/36 (33%)
		LIM3_LPP	508..575	CDD:188821
lmcd1	NP_957364.2	PET_testin	102..189	CDD:193604	15/87 (17%)
		LIM1_Testin_like	230..287	CDD:188726	14/56 (25%)
		LIM	293..>326	CDD:295319	10/32 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900