DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zyx and Lmo7

DIOPT Version :9

Sequence 1:	NP_652015.1	Gene:	Zyx / 317824	FlyBaseID:	FBgn0011642	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_036014595.1	Gene:	Lmo7 / 380928	MGIID:	1353586	Length:	1807	Species:	Mus musculus

Alignment Length:	377	Identity:	77/377 - (20%)
Similarity:	131/377 - (34%)	Gaps:	101/377 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 ADTQINRKTTLDNPAILEQQLEALAYHKLQMEKKGLLGVQA-KPTQPLNSFTKPLSKTLSKSLIY 170
            |:.:...:......|..|.|..|.| .|||.|::....|:. :..:|::|:..|
Mouse  1483 AEAEAKARAEAQARAEAEAQKRAEA-QKLQAERERETSVKIYQYRRPIDSYDLP----------- 1535

  Fly   171 SNLGSVRKEIETLELL-TDETKISASTYSNVNETAMDSSHSSTQKMLSVCTNFI-SDNEKDELPP 233
                  ::|.:|..:| ||.:|..::|  .:|:..::.:.||........|:|. ..::||:.|.
Mouse  1536 ------KREDDTSGMLPTDRSKSRSTT--ELNDPLIEKNGSSKYSERIGATSFSHRSSKKDQAPS 1592

  Fly   234 PPSPE-----------SAVSSSYSELRHATLEFNK-PI---------DYLQNNQTTNPLQIYANQ 277
            ....|           :::.:..|.:|..:...|| ||         :.|.|..:..|.....:.
Mouse  1593 EAELERQQILQEMRKRTSLHNDNSWIRQRSASVNKEPICLPGIMRRGESLDNLDSQRPGSWRQSP 1657

  Fly   278 YAMQHDATGKSSSTYDSIYEPINPRPCVADTLPRESYNLHNSYV---------NDNNPN-ISHEY 332
            :..|......|||..|.    ..|.|.:..|..|......:|.|         :..:|: .||..
Mouse  1658 WHSQPAGVYASSSVQDF----SRPPPQLLSTSNRAYMRNPSSAVPPPAGSVKTSPGSPSPRSHSP 1718

  Fly   333 NISNSIEANQTLYIHGNARTTFYDVNSIHRNDKEGLKNYISIPTEPVQELENYGRCVKCNSRVLG 397
            ::|.|                    .|..||.....|..                |..||: :||
Mouse  1719 SMSQS--------------------GSQLRNRSVSGKRV----------------CSYCNN-ILG 1746

  Fly   398 ESSG--CTAMDQIYHIFCFTCTDCQINLQGKPFYA----LDGKPYCEYDYLQ 443
            :.:.  ...:...||:.||.|..|..:|.|....|    .:.:.||...||:
Mouse  1747 KGAAMIIETLGLSYHLHCFKCVSCGCDLGGSSSGAEVRIRNHQLYCNDCYLR 1798

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	16/58 (28%)
		LIM2_LPP	448..507	CDD:188740
		LIM3_LPP	508..575	CDD:188821
Lmo7	XP_036014595.1	CH_LMO7	14..129	CDD:409126
		DUF4757	242..>314	CDD:406382
		DUF4757	655..802	CDD:406382
		fibronec_FbpA	<829..>930	CDD:411474
		PDZ	1114..1183	CDD:238080
		LIM	1738..1796	CDD:259829	16/58 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900