DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zyx and Lims2

DIOPT Version :9

Sequence 1:	NP_652015.1	Gene:	Zyx / 317824	FlyBaseID:	FBgn0011642	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_006254658.1	Gene:	Lims2 / 361303	RGDID:	1305273	Length:	341	Species:	Rattus norvegicus

Alignment Length:	222	Identity:	59/222 - (26%)
Similarity:	92/222 - (41%)	Gaps:	39/222 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   388 CVKCNSRVLGESSGCTAMDQIYHIFCFTCTDCQINLQGKPFYALDGKPYCEYDYLQTLEK-CSVC 451
            |.:|.:|.........:..::||..||.|..|........||..:|:.|||:|:...... |..|
  Rat    15 CQRCQARFAPTERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGFC 79

  Fly   452 MEPILERILRATGKPYHPQCFTCVVCGKSLDGLLFTVDATNQNYC--------ITDFHKKFAPRC 508
            .|.::.|:::|....:||.||.|.:|...|..|.|..:| .::.|        .....|....||
  Rat    80 GEFVIGRVIKAMNANWHPGCFRCELCDVELADLGFVKNA-GRHLCRPCHNREKAKGLGKFICQRC 143

  Fly   509 --CVCKQPIM--PDPGQEETIRVVALDRSFHLECYKCEDCGLLLSSEA-EGRG---CYPLDDHV- 564
              .:.:||:|  .||              :|.:.:.|..||..|:|:| |.:|   |.|..|.:
  Rat   144 HLAIDEQPLMFKNDP--------------YHPDHFSCSHCGKELTSDARELKGELYCLPCHDKMG 194

  Fly   565 --LCKSC----NAKRVQALTNRMTSEH 585
              :|.:|    ..:.|.||..:...||
  Rat   195 IPICGACRRPIEGRVVNALGKQWHVEH 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	15/52 (29%)
		LIM2_LPP	448..507	CDD:188740	17/66 (26%)
		LIM3_LPP	508..575	CDD:188821	20/81 (25%)
Lims2	XP_006254658.1	LIM1_PINCH	15..73	CDD:188717	16/57 (28%)
		LIM2_PINCH	76..127	CDD:188718	16/51 (31%)
		LIM3_PINCH	140..190	CDD:188719	18/63 (29%)
		LIM4_PINCH	196..249	CDD:188720	7/26 (27%)
		LIM5_PINCH	257..310	CDD:188721
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810