DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zyx and Pph13

DIOPT Version :9

Sequence 1:	NP_652015.1	Gene:	Zyx / 317824	FlyBaseID:	FBgn0011642	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_477330.1	Gene:	Pph13 / 33239	FlyBaseID:	FBgn0023489	Length:	357	Species:	Drosophila melanogaster

Alignment Length:	247	Identity:	52/247 - (21%)
Similarity:	86/247 - (34%)	Gaps:	73/247 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 RGHMP---FRKYLSSEFGVADTQI-----NRK------------------------TTLDNPAIL 123
            |.|.|   ||:.|:....:.:.::     ||:                        .:.|:.|:|
  Fly    31 RTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWRKQEKIGGLGGDYKEGALDLDVSYDDSAVL 95

  Fly   124 EQQLEALAYHKLQMEKKGLLGVQAKPTQPLNSFTKPLSKT-----LSKSLIYSNLGSVRKEIETL 183
            .|...||.       ..|.| :...|.|..||....|..:     :|.|.:..|: .:...|:.|
  Fly    96 GQLDSALG-------GGGTL-LPDTPPQSSNSLDNELKASYGTGAMSPSRLSPNI-FLNLNIDHL 151

  Fly   184 ELLTDETKISA--STYSNVNETAMDSSHSSTQKMLSVCTNFISDNEKDELPP---PPSPESAVSS 243
            .|....:.:|.  |||.       ..:.:.|...:.      |||:..:.||   ...|..|.||
  Fly   152 GLERGGSGLSMEWSTYP-------PQTQAQTHPQMD------SDNQLQQHPPQQHASDPIHAGSS 203

  Fly   244 SYSELRHATLEFNKPIDYLQNNQTTNPLQIYANQYAMQHDATGKSSSTYDSI 295
            |:.:.:....:..      |:|...:|...:|...::  |.| ..||.||.:
  Fly   204 SHHQQQQQQHQQE------QHNPQLHPGLEFAASLSL--DMT-DGSSAYDEM 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737
		LIM2_LPP	448..507	CDD:188740
		LIM3_LPP	508..575	CDD:188821
Pph13	NP_477330.1	Homeobox	14..66	CDD:278475	8/34 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910