DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zyx and LMCD1

DIOPT Version :9

Sequence 1:	NP_652015.1	Gene:	Zyx / 317824	FlyBaseID:	FBgn0011642	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_055398.1	Gene:	LMCD1 / 29995	HGNCID:	6633	Length:	365	Species:	Homo sapiens

Alignment Length:	149	Identity:	40/149 - (26%)
Similarity:	61/149 - (40%)	Gaps:	30/149 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   435 PYCEYDYLQTLEKCSVCM------EPILERILRATGKPYHPQCFTCVVCGKSL-DGLLFTVDAT- 491
            |..|.:|:     |.:|.      .|::........|.:||.||.|..|.:.| |.:.|..|..
Human   235 PSKEVEYV-----CELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAP 294

  Fly   492 --NQNYCITDFHKKFAPRCCVCKQPIMPDPGQEETIRVVALDRSFHLECYKCEDCGLLLSSEAEG 554
              .::||     :...|||..|.:.|..:..|    ||.  |.::|.:.:.||.|..|||    |
Human   295 WCGRHYC-----ESLRPRCSGCDEIIFAEDYQ----RVE--DLAWHRKHFVCEGCEQLLS----G 344

  Fly   555 RGCYPLDDHVLCKSCNAKR 573
            |........:||.:|:..:
Human   345 RAYIVTKGQLLCPTCSKSK 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	2/5 (40%)
		LIM2_LPP	448..507	CDD:188740	16/68 (24%)
		LIM3_LPP	508..575	CDD:188821	19/66 (29%)
LMCD1	NP_055398.1	PET_testin	116..203	CDD:193604
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	200..235		40/149 (27%)
		LIM1_Testin_like	243..300	CDD:188726	14/56 (25%)
		LIM	306..359	CDD:295319	20/62 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900