DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zyx and Fhl5

DIOPT Version :9

Sequence 1:	NP_652015.1	Gene:	Zyx / 317824	FlyBaseID:	FBgn0011642	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001013106.1	Gene:	Fhl5 / 297954	RGDID:	1307056	Length:	284	Species:	Rattus norvegicus

Alignment Length:	206	Identity:	59/206 - (28%)
Similarity:	86/206 - (41%)	Gaps:	21/206 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   384 NYGRCVKCNSRVLGESSGCTAMDQIYHIFCFTCTDCQINLQGKPFYALDGKPYCEYDYL-QTLEK 447
            ||  |.:|...:..:|......::.:|..||.|..|..:|..|||.|.|.:..|...|. :...|
  Rat    39 NY--CEQCKEPIESDSKDLCYKNRHWHEGCFRCNKCHHSLVEKPFVAKDERLLCTDCYSNECSSK 101

  Fly   448 CSVCMEPIL--ERILRATGKPYHPQCFTCVVCGKSLDGLLFTVDATNQNYCITDFHKKFAPRCCV 510
            |..|...|:  .|.:...|..:|..||.|..|.:.: |....:...:.|||:..|.|:||..|..
  Rat   102 CFHCKRTIMPGSRKMEFKGNYWHETCFVCEHCRQPI-GTKPLISKESGNYCVPCFEKEFAHYCNF 165

  Fly   511 CKQPIMPDPGQEETIRVVALDRSFHLECYKCEDCGLLLSSEAEGRGCYPLDDHVLCKSC----NA 571
            ||: ::...|      :...|:.:|.||:.|..|...|..||    ....||...|..|    .|
  Rat   166 CKK-VITSGG------ITFRDQIWHKECFLCSGCRKELYEEA----FMSKDDFPFCLDCYNHLYA 219

  Fly   572 KRVQALTNRMT 582
            |:..|.|..:|
  Rat   220 KKCAACTKPIT 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	15/52 (29%)
		LIM2_LPP	448..507	CDD:188740	18/60 (30%)
		LIM3_LPP	508..575	CDD:188821	19/70 (27%)
Fhl5	NP_001013106.1	LIM	<6..34	CDD:413332
		LIM1_FHL	37..95	CDD:188729	17/57 (30%)
		LIM2_FHL5	102..155	CDD:188812	14/53 (26%)
		LIM	163..214	CDD:413332	16/61 (26%)
		LIM4_FHL	222..277	CDD:188733	3/9 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810