Protein Alignment Zyx and Lpp

DIOPT Version :9

• Sequence 1: NP_652015.1
• Gene: Zyx / 317824
• FlyBaseID: FBgn0011642
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: XP_038944025.1
• Gene: Lpp / 288010
• RGDID: 1310535
• Length: 797
• Species: Rattus norvegicus
• Alignment Length: 684
• Identity: 207/684 - (30%)
• Similarity: 305/684 - (44%)
• Gaps: 149/684 - (21%)

  Fly     4 VAQQLRELS----LPKGDTGSPLVCIGHGKVAKLVAKISNNQN---ASVKRRLDIPPK------- 54
            |.|.:..:|    ||...||.||   ||     :.|::....:   .|:......|||
  Rat   159 VPQLISTMSHPSWLPPRSTGEPL---GH-----VPARMETTHSFGTPSISVSTQQPPKKFAPVVA 215

  Fly    55 PPIKYNEMPQVPSSRQVLCSREPLYSQPLIGVEKTMRGHMPFRKYL-SSEFGVADTQINRKTTLD 118
            |..|||...|.......|....|....|  |...:..||.|....| ...|.|.......||..:
  Rat   216 PKPKYNPYKQPGGEGDFLPPPPPPLEDP--GTIPSGSGHFPPPPPLDEGAFIVQRGNPGGKTLEE 278

  Fly   119 NPAILEQQLEALAYHKLQMEKKGLLGVQAKPTQPLNSFTKPLSKTLS--KSLIYSN---LGSVRK 178
            ..:.|:.::::|......:|.......:|.|....:..:.|:|..::  |.::...   |.:.:|
  Rat   279 RRSSLDAEIDSLTSILADLECSSPYKPRAPPGSSSSIASPPVSTPVTGHKRMVIPQQPPLTATKK 343

  Fly   179 E-------------IETLELLTDETKISASTYSNVNETAMDSSHSSTQKMLSVCTNFISDNEKDE 230
            .             |.||:........|.||.|..:..|.:....|.|.    .|::::.:...:
  Rat   344 SATKPQAIPIPVTPIGTLKPQPQPVPASYSTASTSSRPAFNVQVKSAQP----STHYMTGSSSGQ 404

  Fly   231 LPPP----------------PSPESAVSSSYSELRHATLEFNKPIDYLQN--------------- 264
            :..|                |.|.:...:.|:.:..:..:......|..|
  Rat   405 MYGPGSRSYNTQQVPLSAQCPPPTTCAGTDYAYIPPSGQQAESGFGYTSNQGRYFEPFFAACPSY 469

  Fly   265 --NQTTNPL---QIYANQYAMQ--HDATGKSSSTYDSIYEPINPR----------PCVADTLPRE 312
              ....:|.   |:..|.:..:  :.|.|..:.....:|....|:          ||.....|:|
  Rat   470 GGRNEADPAYGQQVQPNTWKREPGYAAPGAGNQNQPGMYSVSGPKKTYITDPVSAPCAPPVQPKE 534

  Fly   313 SYNLHNSYVNDNNPNISHEYNISNSIEANQTLYIHGNARTTFYDVNSIHRNDKEGLKNYISIPTE 377
            ..             :.::..:.|.::                  :.:|...|.|....:..|:.
  Rat   535 RL-------------VKNQKVLQNVVD------------------DRVHGLRKSGFPAPMGPPSV 568

  Fly   378 P----------------VQELEN------YGRCVKCNSRVLGESSGCTAMDQIYHIFCFTCTDCQ 420
            |                :.::||      :|||.:|...|:||.:|||||||::|:.||||..|.
  Rat   569 PPSFRPEDELEHLTKKMLYDMENPPADDYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCMVCD 633

  Fly   421 INLQGKPFYALDGKPYCEYDYLQTLEKCSVCMEPILERILRATGKPYHPQCFTCVVCGKSLDGLL 485
            |.|:|:||||::.|.|||..|:.|||:||||.:||:|||||||||.|||.|||||:|.:||||:.
  Rat   634 IKLRGQPFYAVEKKAYCEPCYINTLEQCSVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIP 698

  Fly   486 FTVDATNQNYCITDFHKKFAPRCCVCKQPIMPDPGQEETIRVVALDRSFHLECYKCEDCGLLLSS 550
            |||||....:||.||||||||||.|||:||||.||||||:|:|||||.||:.||:|||||.|| |
  Rat   699 FTVDACGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYRCEDCGGLL-S 762

  Fly   551 EAEGRGCYPLDDHVLCKSCNAKRVQALTNRMTSE 584
            |.:.:||||||.|:||||||:.|::.||.:.:::
  Rat   763 EGDNQGCYPLDGHILCKSCNSARIRVLTAKASTD 796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	29/52 (56%)
		LIM2_LPP	448..507	CDD:188740	42/58 (72%)
		LIM3_LPP	508..575	CDD:188821	47/66 (71%)
Lpp	XP_038944025.1	PHA03247	<15..429	CDD:223021	57/283 (20%)
		dnaA	347..>534	CDD:237605	27/190 (14%)
		LIM1_TRIP6	601..654	CDD:188736	29/52 (56%)
		LIM	661..720	CDD:413332	42/58 (72%)
		LIM3_TRIP6	721..786	CDD:188820	46/65 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	95	1.000	Domainoid score	I7220
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001663
OrthoInspector	1	1.000	-	-		otm44547
orthoMCL	1	0.900	-	-		OOG6_108119
Panther	1	1.100	-	-	LDO	PTHR24207
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2600
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.770