Protein Alignment Zyx and rga3

DIOPT Version :9

• Sequence 1: NP_652015.1
• Gene: Zyx / 317824
• FlyBaseID: FBgn0011642
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_594871.1
• Gene: rga3 / 2542306
• PomBaseID: SPAC29A4.11
• Length: 969
• Species: Schizosaccharomyces pombe
• Alignment Length: 616
• Identity: 121/616 - (19%)
• Similarity: 199/616 - (32%)
• Gaps: 218/616 - (35%)

  Fly    80 SQPLIGVEKTMRGHM--------PFRKYLSSEFGVADT----------QINRKTT---------- 116
            ::|::     |.|||        |||.: |..:..:||          |.::||:
pombe   333 AEPIV-----MNGHMRSLHNATSPFRPF-SPSYRSSDTHSPRTRSPNVQTHKKTSSQPSDLSSFA 391

  Fly   117 --LDNPAILEQQLEALAY------HKL----QMEKKGLLGVQAKPTQPLNSFTKPLSKTLSKSLI 169
              |..|.:|..:.....:      |.|    |......||...:...|.|..    |.|.::|..
pombe   392 QLLSPPQVLSPKPNGGGHKSFRHSHSLSETSQQTLVPSLGSNGEYHLPTNDH----SSTPAQSER 452

  Fly   170 YSNLGSVRKEIETLELLTDE--TKISASTYSNVNETAMDSSHSSTQKMLSVCTNFISDNEKDELP 232
            .|::..:|:::|.|..||.:  .::|:||:.|......:...:.....|.:|..|.|..:..:.|
pombe   453 DSDVEELREQLENLTALTKKLSERLSSSTFDNSKFIRTEDKDTVRSAKLEICEKFFSFADVTDDP 517

  Fly   233 PPPSPES----AVSSSY---------SELRHATLEFNKPIDYLQNNQ-------------TTNPL 271
            ....|:.    |.:::|         :|:.:.....|:.:|...|.|             .|..|
pombe   518 TLKDPKHQDLVAAANAYMAMLRESYGTEINNLLERRNELLDDYNNVQKILNESLEASVHLNTKNL 582

  Fly   272 QIY----------------ANQYAMQHDATGKSSSTYDSIYEPINPRPCVADTLPRESYNLHNSY 320
            ::.                .||..::|..|..|.:|..|    |||...|:.          ||.
pombe   583 ELADLNNNLVKQIQHRVPPENQSNLEHTITTSSKNTTSS----INPLTAVSS----------NSG 633

  Fly   321 VNDNNPN-ISHEYNISNSIEANQTLYIHGNARTTFYDVN------SIHRNDKEGLKNYISIPTEP 378
            .:...|. :|...|::..|:....   .|:......|||      |:|...|.         .:|
pombe   634 QSSGRPGPLSPNLNVTTRIDIKGK---KGSMHLQPRDVNRKVPFKSMHTKSKS---------ADP 686

  Fly   379 VQELENYGRCVKCNSRVLGESSGCTAMDQIYHIFCFTCTDCQINLQGKPFYALDGKPYCEYDYLQ 443
            |...|:..:|                 |.::|          :|...||
pombe   687 VVGNEDRTQC-----------------DHVFH----------VNAIFKP---------------- 708

  Fly   444 TLEKCSVCMEPILERILRATGKPYHPQCFTC-VVCGKSLDGLLFTVDATNQNYCIT-DFHKKFAP 506
              .:|.:|.|.:....||         ||.| :.|.......||......:....| ..:.|:.|
pombe   709 --SRCYICSESVWGSELR---------CFHCSISCHSRCLKRLFAESEHEKTMSETVSENSKWMP 762

  Fly   507 RCCVCKQPI-MPDPGQEETIRVVALDRSFHLE----------CYKCEDC-GLLLSSEAEGRGCYP 559
                 :.|. ||.||...|:...:|:....:|          |..|.|. ||      |..|.|.
pombe   763 -----EMPTRMPPPGPSPTMFGRSLENQLKIEGSVLPQVIAMCVSCVDAHGL------EVEGIYR 816

  Fly   560 LDDHVLCKSCNAKRVQALTNRMTS-----EH 585
            :       |.:|.:|:.|.:...:     ||
pombe   817 I-------SGSASQVRVLVDEFENGSIRMEH 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	6/52 (12%)
		LIM2_LPP	448..507	CDD:188740	13/60 (22%)
		LIM3_LPP	508..575	CDD:188821	18/78 (23%)
rga3	NP_594871.1	LIM	18..74	CDD:214528
		LIM	78..128	CDD:259829
		C1	698..743	CDD:237996	15/81 (19%)
		RhoGAP	791..962	CDD:214618	14/63 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900