DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zyx and ceh-14

DIOPT Version :9

Sequence 1:	NP_652015.1	Gene:	Zyx / 317824	FlyBaseID:	FBgn0011642	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_509273.1	Gene:	ceh-14 / 181012	WormBaseID:	WBGene00000438	Length:	351	Species:	Caenorhabditis elegans

Alignment Length:	135	Identity:	39/135 - (28%)
Similarity:	61/135 - (45%)	Gaps:	22/135 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   448 CSVCMEPILER-ILRATGKPYHPQCFTCVVCGKSLDGLLFTVDATNQNYCITDFHKKFAPRCCVC 511
            ||:|.:.|.:| :.:..|:.||..|..|..|...|....|..:  :..||...|:|||..:|..|
Worm    48 CSLCDKKIRDRFVSKVNGRCYHSSCLRCSTCKDELGATCFLRE--DSMYCRAHFYKKFGTKCSSC 110

  Fly   512 KQPIMPDPGQEETIRVVALDRSFHLECYKCEDCGLLLSSEAEGRGCYPL--DDHVLCKS------ 568
            .:.|:||    ..:| .|.:..:|:||::|..|...|.:   |...|.:  |..::||.
Worm   111 NEGIVPD----HVVR-KASNHVYHVECFQCFICKRSLET---GEEFYLIADDARLVCKDDYEQAR 167

  Fly   569 ---CN 570
               ||
Worm   168 DKHCN 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737
		LIM2_LPP	448..507	CDD:188740	19/59 (32%)
		LIM3_LPP	508..575	CDD:188821	20/74 (27%)
ceh-14	NP_509273.1	LIM	48..103	CDD:278823	17/56 (30%)
		LIM2_Lhx3_Lhx4	107..163	CDD:188762	18/63 (29%)
		COG5576	<172..295	CDD:227863	1/1 (100%)
		Homeobox	183..236	CDD:278475
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910