Protein Alignment Zyx and zyx-1

DIOPT Version :9

• Sequence 1: NP_652015.1
• Gene: Zyx / 317824
• FlyBaseID: FBgn0011642
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001254364.1
• Gene: zyx-1 / 174951
• WormBaseID: WBGene00006999
• Length: 647
• Species: Caenorhabditis elegans
• Alignment Length: 643
• Identity: 175/643 - (27%)
• Similarity: 268/643 - (41%)
• Gaps: 157/643 - (24%)

  Fly    52 PPKPPIKYNEMPQVPSSRQVLCSRE-----------------PLYSQPLIGVEKTMRGHMPFRKY 99
            ||.||      |.:||. ::|.||:                 |..|:|.:............||.
 Worm     6 PPPPP------PLLPSG-EILPSRKWKTEDAPRRNNHPAPAPPKPSRPTVDASALQHAAARLRKT 63

  Fly   100 LSSEFGVADTQINRKTTLDNPAILEQQ-----------LEALAYHKLQMEKKGLLGVQAKPT--- 150
            ..:|....|.:......||.|   .||           |:.||..|.:.|      :.:.||
 Worm    64 GYNEPVRGDVENLSDGRLDRP---HQQLPDGDRTYRANLQQLAQPKTRAE------IPSPPTYSN 119

  Fly   151 QP------------LNSFTKPLSKTLSKSLIYSNLGSVRK-EIETLELLTDETKISASTYSNVN- 201
            ||            |:.|.:.....||.:...||...:.| ...||....:::. |..::.|.|
 Worm   120 QPRPLGDFHRDPNALSQFQQSREALLSSTSPTSNYSPINKFSSSTLTQYANKSP-SPPSFGNSNS 183

  Fly   202 ETAMDSSHSSTQKMLSVCTNFISDNEKDELPPPPSPESAVSSSYSEL-----------RHATLEF 255
            |....|.:||..   |..|||.|.::.|:.....:..:..::|.:.|           :...|::
 Worm   184 EATYVSPYSSKH---SYPTNFRSYHKDDDYFNNTATTATTTTSSNSLNENNNSNKYGNKETVLQW 245

  Fly   256 NKPIDYLQNNQTTNPLQIYANQYAMQHDATGKSSSTY-DSIYEPINPRPCVADTLPRESYNLHNS 319
            ::|.|..:..::.:|::   |...|.|:   .|::.| ..:.:|..|.|.:...:.:....|.||
 Worm   246 SEPYDPSKIRRSQSPIR---NAREMIHE---YSTTNYVTEVQQPPPPPPDLYQRMTQARTFLQNS 304

  Fly   320 YVND-NNPNISHEYNISNSIEANQTLYIHGNARTTFYDVNSIHRNDKEG---------LKNYISI 374
            .... .:..::.....:|   .|||..:..::...| |.:.|.:|...|         ::..::.
 Worm   305 LAKQLRDEGLTESQKAAN---RNQTGALSASSSIPF-DASQIVKNSYNGDEVDHLVHQMRTKLNQ 365

  Fly   375 PTEPVQELENYGR--------------------------------CVKCNSRVLGESSGCTAMDQ 407
            |.:....:..|.|                                ||.|...:.|:..||.||:|
 Worm   366 PADTSPSIVQYPRRQAPDSSRANYSATTSTSFSSSTTRKIMNINICVGCGKEITGDQPGCNAMNQ 430

  Fly   408 IYHIFCFTCTDCQINLQGKPFYALDGKPYCEYDYLQTLEKCSVCMEPILERILRATGKPYHPQCF 472
            |:|:.||.|..|...|.|..||.:|.||.||..|..:||||:.|...|.:::|||.|..||..||
 Worm   431 IFHVDCFKCGQCSKTLAGASFYNIDDKPTCEGCYQNSLEKCTACNRAISDKLLRACGGVYHVNCF 495

  Fly   473 TCVVCGKSLDGLLFTVDATNQNYCITDFHKKFAPRCCVCKQPIMPDPGQEETIRVVALDRSFHLE 537
            .|..|.|||||:.||:|..|..:|:..||.||||||.:|.:||:|..|::|::||||:|:|||::
 Worm   496 VCFSCKKSLDGIPFTLDKDNNVHCVPCFHDKFAPRCALCSKPIVPQDGEKESVRVVAMDKSFHVD 560

  Fly   538 CYKCEDCGLLLSSEAEGR----------GCYPLDD------------------HVLCK 567
            ||||||||:.|||:.|..          ||.|.||                  |:.||
 Worm   561 CYKCEDCGMQLSSKKECEFTKCKWFFEYGCQPPDDLDINGGHLELCSGALFIRHLCCK 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	24/52 (46%)
		LIM2_LPP	448..507	CDD:188740	28/58 (48%)
		LIM3_LPP	508..575	CDD:188821	35/88 (40%)
zyx-1	NP_001254364.1	LIM	411..464	CDD:295319	24/52 (46%)
		LIM	471..530	CDD:295319	28/58 (48%)
		LIM	531..595	CDD:295319	30/63 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167088
Domainoid	1	1.000	104	1.000	Domainoid score	I4250
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	245	1.000	Inparanoid score	I2064
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001663
OrthoInspector	1	1.000	-	-		oto19676
orthoMCL	1	0.900	-	-		OOG6_108119
Panther	1	1.100	-	-	LDO	PTHR24207
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2600
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.890