Protein Alignment Zyx and PRICKLE2

DIOPT Version :9

• Sequence 1: NP_652015.1
• Gene: Zyx / 317824
• FlyBaseID: FBgn0011642
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: XP_011531734.1
• Gene: PRICKLE2 / 166336
• HGNCID: 20340
• Length: 966
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 85/365 - (23%)
• Similarity: 126/365 - (34%)
• Gaps: 105/365 - (28%)

  Fly   253 LEFNKPIDYL----QNNQTTNPLQIYANQYAMQHDATGKSSSTYDSIYEPINPR------PCVAD 307
            ||..|.|..|    |.|.|::             |.:|.:...|..:...:.|.      .|
Human    99 LEMEKTISKLMFDFQRNSTSD-------------DDSGCALEEYAWVPPGLKPEQVHQYYSC--- 147

  Fly   308 TLPRESYNLHNSYVNDNNPNI----------SHEYNISNSIEANQTLYIHGNARTTFYDVNSIHR 362
             ||.|..    .|||.....:          .|:         |:..|           .||:..
Human   148 -LPEEKV----PYVNSPGEKLRIKQLLHQLPPHD---------NEVRY-----------CNSLDE 187

  Fly   363 NDKEGLKNYISIPTEPVQELENYGR--------------CVKCNSRVLGESSGCTAM----DQIY 409
            .:|..||.:.|     .::.||.||              |.:|..::.|......|.    ...:
Human   188 EEKRELKLFSS-----QRKRENLGRGNVRPFPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCW 247

  Fly   410 HIFCFTCTDCQINLQGKPFYALDGKPYCEYDYLQTLE-KCSVCMEPIL-ERILRATGKPYHPQCF 472
            |..||.||.|...|....::..|||.||...:.:.|: :|:.|.|.|. :....|.|:.:|.:.|
Human   248 HPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHF 312

  Fly   473 TCVVCGKSLDGLLFTVDATNQNYCITDFHKKFAPRCCVCKQPIMPDPGQEETIRVVALD-RSFHL 536
            .|..|...|.|..: :....:.||...|...:|..|..|.|.|..|.||      :..| :.:|.
Human   313 CCFECETVLGGQRY-IMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQ------MTYDGQHWHA 370

  Fly   537 --ECYKCEDC--GLLLSSEAEGRGCYPLDDHVLC-KSCNA 571
              .|:.|..|  .||      ||...|....:.| ::|:|
Human   371 TETCFCCAHCKKSLL------GRPFLPKQGQIFCSRACSA 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	16/56 (29%)
		LIM2_LPP	448..507	CDD:188740	16/59 (27%)
		LIM3_LPP	508..575	CDD:188821	20/70 (29%)
PRICKLE2	XP_011531734.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810