DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zyx and AgaP_AGAP005138

DIOPT Version :9

Sequence 1:	NP_652015.1	Gene:	Zyx / 317824	FlyBaseID:	FBgn0011642	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_314022.4	Gene:	AgaP_AGAP005138 / 1274816	VectorBaseID:	AGAP005138	Length:	456	Species:	Anopheles gambiae

Alignment Length:	176	Identity:	48/176 - (27%)
Similarity:	71/176 - (40%)	Gaps:	40/176 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   386 GRCVK--CNSRVLGESSGCTAMDQIYHIFCFTCTDCQINLQGKPFYALDGKPYCEYDY--LQTLE 446
            |:|..  |:..::      ..:|..||..|..||.|.|.|....|.. |||.||.:||  |....
Mosquito   151 GQCCGPICDRYIM------KVVDITYHERCLQCTSCSIRLMHSCFMR-DGKLYCRFDYERLYGRN 208

  Fly   447 KCSVCMEPI--LERILRATGKPYHPQCFTCVVCGKSLDGLLFTVDATNQNYCITDFHKKFAPRCC 509
            :|..|.|.|  .|.::||....:|.:||.|||||..|......|...:|.:|..|:.|:
Mosquito   209 RCLGCGEKIGADELVMRALDNVFHLKCFICVVCGVRLQKGDQYVIKQSQLFCRPDYEKE------ 267

  Fly   510 VCKQPIMPDPGQEETIRVVALDRSFHLECYKCEDCGLLLSSEAEGR 555
                              |.:.:.:..:.|.|:|   :..:..:||
Mosquito   268 ------------------VEMFQGYSYDDYCCDD---MFQTRIDGR 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	17/54 (31%)
		LIM2_LPP	448..507	CDD:188740	21/60 (35%)
		LIM3_LPP	508..575	CDD:188821	6/48 (13%)
AgaP_AGAP005138	XP_314022.4	LIM	150..202	CDD:295319	19/57 (33%)
		LIM	210..264	CDD:295319	19/53 (36%)
		homeodomain	296..>341	CDD:238039
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910