DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zyx and fhl5

DIOPT Version :9

Sequence 1:	NP_652015.1	Gene:	Zyx / 317824	FlyBaseID:	FBgn0011642	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001116957.1	Gene:	fhl5 / 100144736	XenbaseID:	XB-GENE-1002465	Length:	282	Species:	Xenopus tropicalis

Alignment Length:	188	Identity:	54/188 - (28%)
Similarity:	79/188 - (42%)	Gaps:	9/188 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   383 ENYGRCVKCNSRVLGESSGCTAMDQIYHIFCFTCTDCQINLQGKPFYALDGKPYCEYDY-LQTLE 446
            |...:|..|.:.::..|.........:|..||.|..|:..:..|||...:.|.||...| .|...
Frog    97 EYSSKCFGCRATIMPGSRKMEYNGSNWHETCFVCQSCREPVGNKPFIPKESKIYCMPCYEKQFAN 161

  Fly   447 KCSVCMEPILERILRATGKPYHPQCFTCVVCGKSLDGLLFTVDATNQNYCITDFHKKFAPRCCVC 511
            :|..|.:.|.:..|....:.:|.:||.|..|.|:|.|...| ......||:..|...:|.:|..|
Frog   162 QCKSCRKAITKGGLSFQEQQWHRECFVCTSCKKNLVGEKST-SRDESPYCVDCFDNLYAKKCAAC 225

  Fly   512 KQPIMPDPGQEETIRVVALDRSFHLECYKCEDCGLLLSSEAEGRGCYPLDDHVLCKSC 569
            .:||   .||.....:...||.:|.:|:.|..|    |....|...:..:|.|||.||
Frog   226 AKPI---TGQGGAKYISFEDRQWHSDCFTCAKC----SKSLVGEKFHTNEDDVLCPSC 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	14/52 (27%)
		LIM2_LPP	448..507	CDD:188740	17/58 (29%)
		LIM3_LPP	508..575	CDD:188821	20/62 (32%)
fhl5	NP_001116957.1	LIM	<6..33	CDD:351770
		LIM1_FHL	37..95	CDD:188729
		LIM2_FHL	102..155	CDD:188731	14/52 (27%)
		LIM3_FHL	163..214	CDD:188732	15/51 (29%)
		LIM4_FHL	222..277	CDD:188733	20/62 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910