DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zyx and lhx1

DIOPT Version :9

Sequence 1:	NP_652015.1	Gene:	Zyx / 317824	FlyBaseID:	FBgn0011642	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001093698.1	Gene:	lhx1 / 100101708	XenbaseID:	XB-GENE-482482	Length:	409	Species:	Xenopus tropicalis

Alignment Length:	203	Identity:	55/203 - (27%)
Similarity:	85/203 - (41%)	Gaps:	45/203 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   388 CVKCNSRVLGESSGCTAMDQIYHIFCFTCTDCQINLQGKPFYALDGKPYCEYDYLQTL-EKCSVC 451
            |..|...:| :......:|:.:|:.|..|.:|:.||..|.| :.:||.||:.|:.:.. .||:.|
Frog     4 CAGCERPIL-DRFLLNVLDRAWHVKCVQCCECKCNLTEKCF-SREGKLYCKNDFFRRFGTKCAGC 66

  Fly   452 MEPI--LERILRATGKPYHPQCFTCVVCGKSLDGLLFTVDATNQNYCITDFHKKFAPRCCVCKQP 514
            .:.|  .:.:.||..|.:|..||||::|.|.|        :|.:...|.| ..||     |||:.
Frog    67 AQGISPSDLVRRARSKVFHLNCFTCMMCNKQL--------STGEELYIID-ENKF-----VCKED 117

  Fly   515 IMPDPG-------QEETIRVVALDRSFHLECYKCEDCGLLLSSEAEGRGCYPL-DDHVLCKSCNA 571
            .:.:..       :...|.|...|.|              ||.|::.    || ||....:|.|.
Frog   118 YLNNNNNNNNAAKENSFISVTGSDPS--------------LSPESQD----PLQDDAKDSESANI 164

  Fly   572 KRVQALTN 579
            ...:|..|
Frog   165 SDKEAGVN 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	16/52 (31%)
		LIM2_LPP	448..507	CDD:188740	19/60 (32%)
		LIM3_LPP	508..575	CDD:188821	16/74 (22%)
lhx1	NP_001093698.1	LIM1_Lhx1_Lhx5	4..55	CDD:188753	16/52 (31%)
		LIM2_Lhx1_Lhx5	63..118	CDD:188761	22/68 (32%)
		Homeobox	186..240	CDD:365835
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910