DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zyx and ablim1a

DIOPT Version :9

Sequence 1:	NP_652015.1	Gene:	Zyx / 317824	FlyBaseID:	FBgn0011642	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_021336151.1	Gene:	ablim1a / 100003558	ZFINID:	ZDB-GENE-080219-41	Length:	803	Species:	Danio rerio

Alignment Length:	307	Identity:	77/307 - (25%)
Similarity:	125/307 - (40%)	Gaps:	79/307 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   305 VADTL---PRESYNLHNSYVNDNNPNISHEYNISNSIEANQTLYIHGNARTTFYDVNSIHRNDKE 366
            ||:.|   |::|......::|.:      :|.::.|:    |...|..        .|.|:.:|.
Zfish    44 VAEVLYLIPKQSVKQQLPFINPD------DYYMTESL----TPVAHTQ--------ESHHQTEKP 90

  Fly   367 GLKNYISIPTEPVQELENYGRCVKCNSRVLGESSGCTAMDQIYHIFCFTCTDCQINLQGKPFYAL 431
            .:                  ||.||.....||.....|  :.:||.||||..|..:|....|:..
Zfish    91 LI------------------RCAKCGELCKGEVLRVQA--KHFHIKCFTCKVCGCDLAQGGFFMK 135

  Fly   432 DGKPYCEYDYLQTLE--KCSVCMEPILERILRATGKPYHPQCFTCVVCGKSL---DGLLFTVDAT 491
            :|:..|..|| |.:.  :|::|.|.:...::.|.||.|||.||.|.:|.:..   |.:.|.....
Zfish   136 NGEYLCTLDY-QRIHGTRCNICGEFVEGEVVTALGKTYHPTCFVCTICKRPFPAGDRVTFNGKDC 199

  Fly   492 NQNYCI---------------TDFHKKFAPRCCVCKQPIMPDPGQEETIRVVALDRSFHLECYKC 541
            ...||.               :::.||.:..|..|.:.|  ..||    .::||:|.:||.|:||
Zfish   200 LCQYCAEPMSPGPTKDVVGPSSEYEKKNSKSCAGCGRDI--KNGQ----ALLALERQWHLGCFKC 258

  Fly   542 EDCGLLLSSEAEGRG----C---YPLDDHVLCKSCNAKRVQALTNRM 581
            :.|..:|:.|...:.    |   |.|...|.|::|.    |.:|.::
Zfish   259 KACAKVLTGEYISKDGAPFCERDYQLQFGVQCEACQ----QFITGKV 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zyx	NP_652015.1	LIM1_LPP	388..441	CDD:188737	17/52 (33%)
		LIM2_LPP	448..507	CDD:188740	19/76 (25%)
		LIM3_LPP	508..575	CDD:188821	22/73 (30%)
ablim1a	XP_021336151.1	LIM1_abLIM	94..145	CDD:188713	17/52 (33%)
		LIM2_abLIM	150..205	CDD:188714	16/54 (30%)
		LIM3_abLIM	231..282	CDD:188715	17/56 (30%)
		LIM4_abLIM	290..345	CDD:188716	4/16 (25%)
		AbLIM_anchor	370..767	CDD:318423
		VHP	768..803	CDD:128458
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910