Protein Alignment CG12116 and NRE1

DIOPT Version :10

• Sequence 1: NP_572481.1
• Gene: CG12116 / 31782
• FlyBaseID: FBgn0030041
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_012301.3
• Gene: NRE1 / 854853
• SGDID: S000001474
• Length: 254
• Species: Saccharomyces cerevisiae
• Alignment Length: 281
• Identity: 58/281 - (20%)
• Similarity: 106/281 - (37%)
• Gaps: 64/281 - (22%)

  Fly    14 LVLSGSSNPLGQSLALEFCRRLATGSLALILDEDQEQLRELENHLRSELKTENVK--------VT 70
            ::::|.|..:|:|:.          .:...||:|    ..:....|||...:.:|        ..
Yeast     5 ILVTGVSRGIGKSIV----------DVLFSLDKD----TVVYGVARSEAPLKKLKEKYGDRFFYV 55

  Fly    71 IGKLDKDHSNGVQLMEQALMDNFMADKDNQRFERSIILHNEGKAATHMLLEPQSD------DDWK 129
            :|.:.:| |...||:..|:..:...|.         ::.|.|      :|||..:      :.||
Yeast    56 VGDITED-SVLKQLVNAAVKGHGKIDS---------LVANAG------VLEPVQNVNEIDVNAWK 104

  Fly   130 AYVQQQLYAPVALNQTWLQSKHLERVEKLAVNVTSSLMVRPLVHAGLLCSCKRARDMYFRAMAAE 194
            .......::.|:|  ..:....|::.....|.|:|..........|...|.|.|.:.:...:|.|
Yeast   105 KLYDINFFSIVSL--VGIALPELKKTNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE 167

  Fly   195 EYRFGVHVLSFSPGLMDTHEGQCDVNGNRITPADLIA-----------TKQLLQLPRIKPCQATL 248
            |.:  |..::.:||::|| :.|.::..| :.|:.:.|           ..|||.........|.|
Yeast   168 ERQ--VKAIAVAPGIVDT-DMQVNIREN-VGPSSMSAEQLKMFRGLKENNQLLDSSVPATVYAKL 228

  Fly   249 KLINILEEISFVSGHDVDYYD 269
            .|..|.:.   |:|..:.|.|
Yeast   229 ALHGIPDG---VNGQYLSYND 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12116	NP_572481.1	SPR-like_SDR_c	13..269	CDD:187625	57/279 (20%)
NRE1	NP_012301.3	SPR-like_SDR_c	4..246	CDD:187625	57/279 (20%)