DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32006 and FOXL2

DIOPT Version :9

Sequence 1:	NP_726538.1	Gene:	CG32006 / 317817	FlyBaseID:	FBgn0052006	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_075555.1	Gene:	FOXL2 / 668	HGNCID:	1092	Length:	376	Species:	Homo sapiens

Alignment Length:	109	Identity:	46/109 - (42%)
Similarity:	62/109 - (56%)	Gaps:	16/109 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 DVTEKPPFNYSHIIGMAMLQNG--RITLQQLCSWIEAKFAFFRVRKK-WNNSIRHNLSLHHCFRN 203
            |..:|||::|..:|.||:.::.  |:||..:..:|.|||.|:...|| |.|||||||||:.||..
Human    50 DPAQKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIK 114

  Fly   204 RKREERG--KGGYWELGVDPKKCD--------RKRIRNRKIFHP 237
            ..||..|  ||.||.|  || .|:        |:|.|.::.|.|
Human   115 VPREGGGERKGNYWTL--DP-ACEDMFEKGNYRRRRRMKRPFRP 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32006	NP_726538.1	FH	146..217	CDD:294049	36/75 (48%)
FOXL2	NP_075555.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..53		1/2 (50%)
		Forkhead	53..139	CDD:365978	40/88 (45%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	276..342
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000