DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32006 and FOXB2

DIOPT Version :9

Sequence 1:	NP_726538.1	Gene:	CG32006 / 317817	FlyBaseID:	FBgn0052006	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_001013757.1	Gene:	FOXB2 / 442425	HGNCID:	23315	Length:	432	Species:	Homo sapiens

Alignment Length:	159	Identity:	42/159 - (26%)
Similarity:	70/159 - (44%)	Gaps:	37/159 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 EKPPFNYSHIIGMAMLQNGR--ITLQQLCSWIEAKFAFFRVR-KKWNNSIRHNLSLHHCFRN--R 204
            :|||::|..:..||:..:..  :.|..:..:|..:|.::|.. ::|.||:|||||.:.||..  |
Human    12 QKPPYSYISLTAMAIQHSAEKMLPLSDIYKFIMERFPYYREHTQRWQNSLRHNLSFNDCFIKIPR 76

  Fly   205 KREERGKGGYWELGVDPKKC-----DRKRIRNRKIFHPTQNQTAKLQYEHLTEIQQAKSARKNHS 264
            :.::.|||.:|.|..|   |     :...:|.||.|                     |..|.:|:
Human    77 RPDQPGKGSFWALHPD---CGDMFENGSFLRRRKRF---------------------KVLRADHT 117

  Fly   265 RHIKKSKTSSLPETSEANIFNVVPHKKHN 293
             |:....|.|.|......  ::.||..|:
Human   118 -HLHAGSTKSAPGAGPGG--HLHPHHHHH 143

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32006	NP_726538.1	FH	146..217	CDD:294049	25/75 (33%)
FOXB2	NP_001013757.1	FH	13..101	CDD:214627	28/90 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	118..220		7/28 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	413..432
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11829
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010