DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32006 and FOXI3

DIOPT Version :10

Sequence 1:NP_726538.1 Gene:CG32006 / 317817 FlyBaseID:FBgn0052006 Length:443 Species:Drosophila melanogaster
Sequence 2:NP_001129121.1 Gene:FOXI3 / 344167 HGNCID:35123 Length:420 Species:Homo sapiens


Alignment Length:112 Identity:40/112 - (35%)
Similarity:64/112 - (57%) Gaps:17/112 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   135 LASKYETDVTEKPPFNYSHIIGMAMLQNG---RITLQQLCSWIEAKFAFF-RVRKKWNNSIRHNL 195
            :||:.:.....:||::||.:|.|| :|:.   ::||..:..::...|.|: |.:..|.|||||||
Human   134 MASREDLMKMVRPPYSYSALIAMA-IQSAPERKLTLSHIYQFVADSFPFYQRSKAGWQNSIRHNL 197

  Fly   196 SLHHCFRN--RKREERGKGGYWELGVDPKKCDR-------KRIRNRK 233
            ||:.||:.  |..::.|||.||.|  || .|::       :|.|.|:
Human   198 SLNDCFKKVPRDEDDPGKGNYWTL--DP-NCEKMFDNGNFRRKRKRR 241

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32006NP_726538.1 Forkhead 146..217 CDD:459732 31/76 (41%)
FOXI3NP_001129121.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 103..122
FH_FOXI1 142..241 CDD:410827 37/102 (36%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 234..306 3/8 (38%)
Nuclear localization signal. /evidence=ECO:0000269|PubMed:37041148 235..241 2/5 (40%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 364..396
9aaTAD. /evidence=ECO:0000250|UniProtKB:D3Z120 406..414
Blue background indicates that the domain is not in the aligned region.

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