DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32006 and FOXB1

DIOPT Version :9

Sequence 1:	NP_726538.1	Gene:	CG32006 / 317817	FlyBaseID:	FBgn0052006	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_036314.2	Gene:	FOXB1 / 27023	HGNCID:	3799	Length:	325	Species:	Homo sapiens

Alignment Length:	177	Identity:	53/177 - (29%)
Similarity:	79/177 - (44%)	Gaps:	37/177 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 EKPPFNYSHIIGMAMLQNGR--ITLQQLCSWIEAKFAFFRVR-KKWNNSIRHNLSLHHCFRN--R 204
            :|||::|..:..||:..:..  :.|.::..:|..:|.::|.. ::|.||:|||||.:.||..  |
Human    12 QKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPR 76

  Fly   205 KREERGKGGYWELGVDPKKCD----------RKRIRNRKIFHPTQNQTA-KLQYEHLTEIQQAK- 257
            :.::.|||.:|.|  .|...|          |||.:..|..|...::.| ..||..    ||||
Human    77 RPDQPGKGSFWAL--HPSCGDMFENGSFLRRRKRFKVLKSDHLAPSKPADAAQYLQ----QQAKL 135

  Fly   258 --SARKNHSRHIKKSKTSSLPETSEA--NIFNVVPHK--KHNIADEN 298
              ||......|        ||:...|  |:..|....  ||..|.||
Human   136 RLSALAASGTH--------LPQMPAAAYNLGGVAQPSGFKHPFAIEN 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32006	NP_726538.1	FH	146..217	CDD:294049	25/75 (33%)
FOXB1	NP_036314.2	FH_FOXB2	1..110	CDD:410817	31/99 (31%)
FOXB1	NP_036314.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	284..325
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11829
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010