DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32006 and FOXI1

DIOPT Version :9

Sequence 1:	NP_726538.1	Gene:	CG32006 / 317817	FlyBaseID:	FBgn0052006	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_036320.2	Gene:	FOXI1 / 2299	HGNCID:	3815	Length:	378	Species:	Homo sapiens

Alignment Length:	251	Identity:	71/251 - (28%)
Similarity:	96/251 - (38%)	Gaps:	84/251 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 KPPFNYSHIIGMAM--LQNGRITLQQLCSWIEAKFAFFRVRKK-WNNSIRHNLSLHHCFRN--RK 205
            :||::||.:|.||:  ..:.|:||.|:..::...|.|:...|. |.|||||||||:.||:.  |.
Human   123 RPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRD 187

  Fly   206 REERGKGGYWELGVDPKKCDR-------KRIRNRKIFHPTQNQTAKLQYEHLTEIQQAKSARKNH 263
            .::.|||.||.|  || .|::       :|.|.||  ....:.||.|..|
Human   188 EDDPGKGNYWTL--DP-NCEKMFDNGNFRRKRKRK--SDVSSSTASLALE--------------- 232

  Fly   264 SRHIKKSKT-SSLPETSEANIFNVVPHKKHNIADENDGQRQLQTINKDDILKKKSELDTIVSSTE 327
                   || ||||..|.                        :|....|||...|...|..|..:
Human   233 -------KTESSLPVDSP------------------------KTTEPQDILDGASPGGTTSSPEK 266

  Fly   328 SFLTESQNLNCFNSHKTDTTN-------------TP-ISAE------KNFCTFNNF 363
            ..........|.||..:..|.             || :|.|      :|..|||:|
Human   267 RPSPPPSGAPCLNSFLSSMTAYVSGGSPTSHPLVTPGLSPEPSDKTGQNSLTFNSF 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32006	NP_726538.1	FH	146..217	CDD:294049	32/75 (43%)
FOXI1	NP_036320.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		FH	123..211	CDD:214627	36/90 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	208..278		22/117 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810