DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32006 and unc-130

DIOPT Version :9

Sequence 1:	NP_726538.1	Gene:	CG32006 / 317817	FlyBaseID:	FBgn0052006	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_496411.1	Gene:	unc-130 / 174721	WormBaseID:	WBGene00006853	Length:	333	Species:	Caenorhabditis elegans

Alignment Length:	194	Identity:	55/194 - (28%)
Similarity:	90/194 - (46%)	Gaps:	30/194 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 NSKRNTEPTHKSRVHDKQIKMFYSTR----------ENTDKISHIILEANAQKSITKRPTASERF 118
            ::.|.:||:..:.|.:..:|...|.:          |:.|.:.  :.:||.:...|.....|...
Worm    38 SNTRLSEPSTSASVLEHDLKFGESRKRSRSLGDEPTEDEDGVP--VRKANKRNHSTSSAADSSSD 100

  Fly   119 EIFVNKIKRDLTEYEKLASKYETDVTEKPPFNYSHIIGMAMLQN--GRITLQQLCSWIEAKFAFF 181
            :...:....|.|. .|..|.:......|||::|..:|.|::|.:  .::||.::|.:|..||.::
Worm   101 DAKDDDDDDDSTS-RKSMSGHRKSSHAKPPYSYIALIAMSILNSPEKKLTLSEICEFIINKFEYY 164

  Fly   182 RVR-KKWNNSIRHNLSLHHCFRN--RKREERGKGGYWELGVDPKKCD---------RKRIRNRK 233
            :.: ..|.|||||||||:.||..  |.....|||.||.|  || .|:         |:|.|.:|
Worm   165 KEKFPAWQNSIRHNLSLNDCFVKVARGPGNPGKGNYWAL--DP-NCEDMFDNGSFLRRRKRYKK 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32006	NP_726538.1	FH	146..217	CDD:294049	31/75 (41%)
unc-130	NP_496411.1	COG5025	<126..330	CDD:227358	39/103 (38%)
unc-130	NP_496411.1	Forkhead	127..212	CDD:365978	35/87 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810