DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32006 and Foxc1

DIOPT Version :9

Sequence 1:NP_726538.1 Gene:CG32006 / 317817 FlyBaseID:FBgn0052006 Length:443 Species:Drosophila melanogaster
Sequence 2:NP_032618.2 Gene:Foxc1 / 17300 MGIID:1347466 Length:553 Species:Mus musculus


Alignment Length:102 Identity:42/102 - (41%)
Similarity:59/102 - (57%) Gaps:17/102 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   146 KPPFNYSHIIGMAMLQNG---RITLQQLCSWIEAKFAFFRVRKK-WNNSIRHNLSLHHCFRNRKR 206
            |||::|..:|.|| :||.   :|||..:..:|..:|.|:|..|: |.|||||||||:.||....|
Mouse    78 KPPYSYIALITMA-IQNAPDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPR 141

  Fly   207 EER--GKGGYWELGVDPKKCD--------RKRIRNRK 233
            :::  |||.||.|  ||...:        |:|.|.:|
Mouse   142 DDKKPGKGSYWTL--DPDSYNMFENGSFLRRRRRFKK 176

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32006NP_726538.1 FH 146..217 CDD:294049 35/76 (46%)
Foxc1NP_032618.2 Required for transcriptional activation. /evidence=ECO:0000250|UniProtKB:Q12948 1..51
FH 78..166 CDD:214627 38/90 (42%)
Nuclear localization signal 1 (NLS 1). /evidence=ECO:0000250|UniProtKB:Q12948 78..93 7/15 (47%)
Nuclear localization signal 2 (NLS 2). /evidence=ECO:0000250|UniProtKB:Q12948 168..176 3/7 (43%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 173..326 2/4 (50%)
Required for transcriptional inhibition. /evidence=ECO:0000250|UniProtKB:Q12948 217..366
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 356..393
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 420..466
Required for transcriptional activation. /evidence=ECO:0000250|UniProtKB:Q12948 466..553
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.810

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