DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32006 and Foxc2

DIOPT Version :9

Sequence 1:	NP_726538.1	Gene:	CG32006 / 317817	FlyBaseID:	FBgn0052006	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_038547.2	Gene:	Foxc2 / 14234	MGIID:	1347481	Length:	494	Species:	Mus musculus

Alignment Length:	155	Identity:	53/155 - (34%)
Similarity:	77/155 - (49%)	Gaps:	27/155 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 KPPFNYSHIIGMAMLQNG---RITLQQLCSWIEAKFAFFRVRKK-WNNSIRHNLSLHHCFRNRKR 206
            |||::|..:|.|| :||.   :|||..:..:|..:|.|:|..|: |.|||||||||:.||....|
Mouse    71 KPPYSYIALITMA-IQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPR 134

  Fly   207 EER--GKGGYWELGVDPKKCDR----KRIRNRKIFHPTQNQTAKLQYEHLTE--IQQAKSA---- 259
            :::  |||.||.|  ||...:.    ..:|.|:.|........|.:..||.|  ...||.|
Mouse   135 DDKKPGKGSYWTL--DPDSYNMFENGSFLRRRRRFKKKDVPKDKEERAHLKEPPSTTAKGAPTGT 197

  Fly   260 ------RKNHSRHIKKSKTSS--LP 276
                  ::...:.:.||:.:|  ||
Mouse   198 PVADGPKEAEKKVVVKSEAASPALP 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32006	NP_726538.1	FH	146..217	CDD:294049	35/76 (46%)
Foxc2	NP_038547.2	FH	71..159	CDD:214627	38/90 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	166..213		8/46 (17%)
		EBP50_C	167..>257	CDD:286142	13/56 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	233..267
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	381..422
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810