Protein Alignment anne and SERCA

DIOPT Version :9

• Sequence 1: NP_001096849.1
• Gene: anne / 317815
• FlyBaseID: FBgn0052000
• Length: 1451
• Species: Drosophila melanogaster
• Sequence 2: NP_726381.1
• Gene: SERCA / 49297
• FlyBaseID: FBgn0263006
• Length: 1020
• Species: Drosophila melanogaster
• Alignment Length: 1211
• Identity: 246/1211 - (20%)
• Similarity: 409/1211 - (33%)
• Gaps: 401/1211 - (33%)

  Fly   320 QRGLPVHEQISRRIVFGDNEITVPLRDFKTL--LFLEVLNPFYV-FQLFSVILWF---------- 371
            :|||.:.:..:.:..:|.||:  |..:.|::  |.||..:...| ..|.:.|:.|
  Fly    21 ERGLTLDQIKANQKKYGPNEL--PTEEGKSIWQLVLEQFDDLLVKILLLAAIISFVLALFEEHEE 83

  Fly   372 TYDYYYYACVILLMSVFGITVSVLQTKKNQ---DVLQKTVYNTGNAWVVDHKGLSKELPTRAIVP 433
            |:..:....||||:.:....|.|.|.:..:   :.|::.....|.....|..|:.| :..:.|||
  Fly    84 TFTAFVEPLVILLILIANAVVGVWQERNAESAIEALKEYEPEMGKVVRQDKSGIQK-VRAKEIVP 147

  Fly   434 GDIIEIPSSGCTLHCD---AILISGNCILDESMLTGESVPVTK--TPLPSKRDMIFDKTEHARHT 493
            ||::|: |.|..:..|   ..:.|....:|:|:||||||.|.|  ..:|..|.:..||    ::.
  Fly   148 GDLVEV-SVGDKIPADIRITHIYSTTLRIDQSILTGESVSVIKHTDAIPDPRAVNQDK----KNI 207

  Fly   494 LFCGTKVIQTRYIGSKKVLAFVINTGNITAKG----ELIRSILYPPPVDYKFEQDSYKFIQFLAI 554
            ||.||.|      .:.|....||.||..||.|    |:..:.....|:..|.::...:..:.:::
  Fly   208 LFSGTNV------AAGKARGVVIGTGLSTAIGKIRTEMSETEEIKTPLQQKLDEFGEQLSKVISV 266

  Fly   555 IACVGFIYTLVTKILRGTDPV-------------KIAVESLDLITIVVPPALPAAMTVGRFYAQK 606
            | ||. ::.:  .|....||.             ||||.   |....:|..|||.:|.......:
  Fly   267 I-CVA-VWAI--NIGHFNDPAHGGSWIKGAIYYFKIAVA---LAVAAIPEGLPAVITTCLALGTR 324

  Fly   607 RLKTSEIFCISPRSINVAGSINCCCFDKTGTLTEDGLDMWGVVPKSSTNQFQIPLKSVDRLPFDH 671
            |:........|..|:...|..:..|.|||||||              |||.     ||.|:
  Fly   325 RMAKKNAIVRSLPSVETLGCTSVICSDKTGTLT--------------TNQM-----SVSRM---- 366

  Fly   672 FLFGMVTCHSITILNGRMMGDPLDLKMFESTGWELEDSNNIPDTEKYGILYPTILRQPRGGLSGM 736
            |:|..|..:..:.|...|.|     ..:|..|....:...|...:     |.|:  |....:..|
  Fly   367 FIFDKVEGNDSSFLEFEMTG-----STYEPIGEVFLNGQRIKAAD-----YDTL--QELSTICIM 419

  Fly   737 AETESGSKNEIKRQ-SSVDDLLATVGISPSQKNFDHGIVREFPFTSALQRMSVVTRCLSD----- 795
            ....:...||.|:. ..|.:...|..|..::|.....:.:     |.|.|.|....|..:
  Fly   420 CNDSAIDYNEFKQAFEKVGEATETALIVLAEKLNSFSVNK-----SGLDRRSAAIACRGEIETKW 479

  Fly   796 ------------QVFNVYC----------------KGSPEMLKKLC------------------K 814
                        :..:.||                ||:||.:.:.|                  |
  Fly   480 KKEFTLEFSRDRKSMSSYCTPLKASRLGTGPKLFVKGAPEGVLERCTHARVGTTKVPLTSALKAK 544

  Fly   815 PQSLPDNYSQQLSEFAKKGYRIIAIAFKALSHK---MNYTKVQRLSREEVENNMEFLGFVILENR 876
            ..:|...|..     .:...|.:|:|......|   |:.....:..:.||  |:.|:|.|   ..
  Fly   545 ILALTGQYGT-----GRDTLRCLALAVADSPMKPDEMDLGDSTKFYQYEV--NLTFVGVV---GM 599

  Fly   877 LKPDTTKVINAL---NAAKIRTIMITGDNILTAISVARDCGIVSPSQSVITVHADPIGDSANIQT 938
            |.|...:|.:::   .||.||.|:|||||..||.::.|..|:.:..:       |..|.|
  Fly   600 LDPPRKEVFDSIVRCRAAGIRVIVITGDNKATAEAICRRIGVFAEDE-------DTTGKS----- 652

  Fly   939 NTGTECNFDNSSDKHYKLHYTLDLGSKTSRAYLFKSCFNSNLFDPETPEFTAQVGKTIFHMESTN 1003
                                                 ::...||
  Fly   653 -------------------------------------YSGREFD--------------------- 659

  Fly  1004 SLVNESTSSYAESGLPTSDSLASVKTIDTWTHNDAELGIKHTPDESWRRQECIFAMDGKTWQIVK 1068
                                                                             
  Fly   660 ----------------------------------------------------------------- 659

  Fly  1069 DYFPEEMEILLTRGSIYARMSPDQKQALVIELQNLDYCVAMCGDGANDCGALKVAHAGISLSE-- 1131
            |..|.|.:..:.|..:::|:.|..|..:|..||:::...||.|||.||..|||.|..||::..
  Fly   660 DLSPTEQKAAVARSRLFSRVEPQHKSKIVEFLQSMNEISAMTGDGVNDAPALKKAEIGIAMGSGT 724

  Fly  1132 TEASIASPFTSRNPTISAVLKVIKEGRAALVTSFGIFKYMAAYSLVQFISVMI--LYSIDSNLTD 1194
            ..|..|:.....:...|:::..::||||.........:|:.:.::.:.:|:.:  ...:...|..
  Fly   725 AVAKSAAEMVLADDNFSSIVSAVEEGRAIYNNMKQFIRYLISSNIGEVVSIFLTAALGLPEALIP 789

  Fly  1195 KQYLYVDLGLISIFAFFFGKTESFDGMLVEQVPLSSLISSTPLASLLLHLTVVTAFQVTCWVHLH 1259
            .|.|:|:|                   :.:.:|.::|..:.|...::
  Fly   790 VQLLWVNL-------------------VTDGLPATALGFNPPDLDIM------------------ 817

  Fly  1260 QQPWFKAFEPADEDHLGCFENYTMFCISSFQYIILA---------FVFSKGAPYRKPLWSNWPL- 1314
            ::|..||.|       |....:..|...:..:.:.|         ||||.    ..|..|.|.|
  Fly   818 EKPPRKADE-------GLISGWLFFRYMAIGFYVGAATVGAAAWWFVFSD----EGPKLSYWQLT 871

  Fly  1315 ----CL------------------AFIVNLCIIVYL-VLYPSDWVASFFQLI-VPPTMRFRYVML 1355
                ||                  |..:.|.::|.: :|...:.::....|| :||....  .::
  Fly   872 HHLSCLGGGDEFKGVDCKIFSDPHAMTMALSVLVTIEMLNAMNSLSENQSLITMPPWCNL--WLI 934

  Fly  1356 AYGAASFICHIFVESFLVEYL-----VFKKYQVKREKNWVT 1391
            ...|.||..|     |::.|:     ||:...:..|: |:|
  Fly   935 GSMALSFTLH-----FVILYVDVLSTVFQVTPLSAEE-WIT 969

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
anne	NP_001096849.1	P5-ATPase	158..291	CDD:289194
		P-ATPase-V	173..1355	CDD:273738	235/1168 (20%)
		E1-E2_ATPase	381..621	CDD:278548	70/264 (27%)
		Cation_ATPase	<758..813	CDD:289987	14/87 (16%)
		HAD_like	<1087..1137	CDD:304363	20/51 (39%)
SERCA	NP_726381.1	P-type_ATPase_SERCA	5..989	CDD:319778	246/1211 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438607
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840