Protein Alignment anne and SPoCk

DIOPT Version :9

• Sequence 1: NP_001096849.1
• Gene: anne / 317815
• FlyBaseID: FBgn0052000
• Length: 1451
• Species: Drosophila melanogaster
• Sequence 2: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Alignment Length: 1204
• Identity: 241/1204 - (20%)
• Similarity: 448/1204 - (37%)
• Gaps: 358/1204 - (29%)

  Fly   229 HVKQIQVLTS-------SNLKTLLEKEQQSIERTHIECDHVENVLQLSVHFTSAQFKKCSSIRIF 286
            |||..:.:..       :::|...|.::.::::.:      .|::|..:..|.
  Fly    56 HVKDSRAVPQNVKPGKVADMKDCKEPDEDNVDQQN------GNIIQTGLTLTP------------ 102

  Fly   287 RCKQLVYAWNNNTNRFQRING-LDLNIPCSYYHQQRGLPVHEQISRRIVFGDNEITVPLRDFKTL 350
              :.|:....::|:....:.| |.:::       :.||...|...|..:.|.||:.:...|....
  Fly   103 --EMLLSTSESSTHSASEVAGRLQVDV-------RTGLKWTEAKYRAKIIGHNELLLVAEDPTWK 158

  Fly   351 LFLEVL-NPFYVFQLFSVILWFTYDYYYYACVILLMSVFGITVSVLQTKKNQDVLQKTVYNTGNA 414
            .::|.. ||..:..|.|.::......:..|..|.:..:..:||:.:|..:::..|::
  Fly   159 KYIEQFRNPLILLLLGSALVSVIMKQFDDAVSITIAILIVVTVAFIQEYRSEKSLEE-------- 215

  Fly   415 WVVDHKGLSKELP---------------TRAIVPGDIIEIPSSGCTLHCDAILISG-NCILDESM 463
                   |.|.:|               .|.:|||||:.: :.|..:..|..|... :..:|||.
  Fly   216 -------LKKLVPPECHCLREGRLDTFLARELVPGDIVHL-NVGDRVPADVRLFEAVDLSIDESS 272

  Fly   464 LTGESVPVTKTPLPSKRDMIFDKT---EHA--RHTLFCGTKVIQTRYIGSKKVLAFVINTGNITA 523
            .|||:.|..|.     .|::.:.|   :|:  ::..|.||.|    ..|:.|  ..|::||..:.
  Fly   273 FTGETEPARKI-----TDVLLNNTNVKDHSNMKNIAFMGTLV----RCGNGK--GIVVSTGERSE 326

  Fly   524 KGELIRSIL--------YPPPVDYKFEQDSYKFIQFLAIIACVGFIYTLVTKILRGTDPVKIAVE 580
            .||:.:.:.        ....:|....|.|:.....:.:|..:|:        |:|....::...
  Fly   327 FGEVFKMMQAEEAPKTPLQKSMDILGAQLSFYSFLIIGVIMLLGW--------LQGKPLSEMFNI 383

  Fly   581 SLDLITIVVPPALPAAMTVGRFYAQKRL-KTSEIFCISPRSINVAGSINCCCFDKTGTLTE---- 640
            |:.|....:|..||..:||.......|: |.:.|....| ::...|.:|..|.|||||||:
  Fly   384 SVSLAVAAIPEGLPIVVTVTLALGVMRMAKRNSIVKKLP-TVETLGCVNVICSDKTGTLTKNEMT 447

  Fly   641 -------DGLDMWGVVPKSSTNQFQIPLKSVDRLP-----FDHFLFGMVTCHSITILNGRMMGDP 693
                   ||. |..|......:|.:|.::..:.:.     ..:.|.....|::..|.||.::|.|
  Fly   448 ATIIITSDGY-MADVTGAGYNDQGEIHIRHCNNVEMAKTNITNLLEIGAVCNNAYIQNGTLLGQP 511

  Fly   694 LDLKMFESTGWELEDSNNIPDTEKYGILYPTILRQPRGGLSGMAETESGSKNEIKRQSSVDDLLA 758
            .:                       |.|....::      :||..|   ::|.::
  Fly   512 TE-----------------------GALVAVAMK------NGMYAT---AENYVR---------- 534

  Fly   759 TVGISPSQKNFDHGIVREFPFTSALQRMSVVTRCL------SDQVFNVYCKGSPEMLKKLCK--- 814
                           ::|:||:|..:.|:|  :|:      .:::|  :.||:.|.|...|.
  Fly   535 ---------------IQEYPFSSEQKMMAV--KCIHKYNNNKEEIF--FAKGALETLLPQCTKYQ 580

  Fly   815 --PQSLP---DNYSQQLS---EFAKKGYRIIAIAFKALSHKMNYTKVQRLSREEVENNMEFLGFV 871
              .|::|   .|.::.|:   |..:||.|::|:| |..|.:                ::.:.|.|
  Fly   581 FGTQTVPLTKQNEAEFLAEAYEIGRKGLRVLALA-KGRSMQ----------------DLIYCGLV 628

  Fly   872 ILENRLKPDTTKVINALNAAKIRTIMITGDNILTAISVARDCGIVSPSQ--SVITVHADPIGDSA 934
            .:.:..:|...:.|..|..:.:|..|:|||...||::       :.||:  ..:..||.|...:|
  Fly   629 GITDPPRPLVRESIEMLMQSGVRVKMVTGDAQETALA-------IDPSRRLQAVPTHAIPAWPTA 686

  Fly   935 -NIQTNTGTECNFDNSSDKHYKLHYTLDLGSKTSRAYLFKSCFNSNLFDPETPEFTAQVGKTIFH 998
             .:...:.:.|                              |
  Fly   687 GGVPLCSASAC------------------------------C----------------------- 698

  Fly   999 MESTNSLVNESTSSY----AESGLPTSDSLASVKTIDTWTHNDAELGIKHTPDESWRRQECIFAM 1059
              |||.|.|.....|    |:.|||.  ..|::..|||..|.                     .:
  Fly   699 --STNCLENAMKEIYLTALAQQGLPL--VTANLIGIDTIHHQ---------------------TL 738

  Fly  1060 DGKTWQIVKDYFPEEMEILLTRGSIYARMSPDQKQALVIELQNLDYCVAMCGDGANDCGALKVAH 1124
            .|:....:.::   :::.:....|::.|:||..|..:|..||.....|.|.|||.||..|||.|.
  Fly   739 SGQEMDQMNEH---QLDKVANNVSVFYRVSPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALKKAD 800

  Fly  1125 AGISLSETEASI---ASPFTSRNPTISAVLKVIKEGRAAL--VTSFGIFKYMAAYSLVQFISVMI 1184
            .||::.:....:   |:.....|.....::..|:||:...  :.:|..|:...:.:.:..|::..
  Fly   801 IGIAMGKNGTDVCKEAADMILVNDDFHTIIAAIEEGKGIFYNIRNFVRFQLSTSIAALALIALAT 865

  Fly  1185 LYSIDSNLTDKQYLYVDLGLISIFAFFFGKTESFDGMLVEQVPLS---SLISSTPLASLLLHLTV 1246
            |..|.:.|...|.|::::.:....|...| .|..|..:::|.|.:   .:|:.:.:.::||..::
  Fly   866 LMDIANPLNAMQILWINIIMDGPPAQSLG-VEPVDHDVLKQKPRNVKQPMITKSVVVNVLLSASI 929

  Fly  1247 VTAFQVTCWVHLHQQPWFKAFEPADEDHLG-----------CFENYTMF----CISSFQYIILAF 1296
            :..  .|.||...        |.|| ..||           ||..:.||    |.|..:     .
  Fly   930 IVL--GTLWVFQR--------EMAD-GTLGKTKRDTTMTFTCFVFFDMFNALSCRSQTK-----S 978

  Fly  1297 VFSKGAPYRKPLWSN--WPLCLAF-IVNLCIIVY 1327
            ||:.|      |.:|  :.|.:|| |:...::||
  Fly   979 VFTIG------LTTNRMFLLAVAFSIIGQMLVVY 1006

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
anne	NP_001096849.1	P5-ATPase	158..291	CDD:289194	8/68 (12%)
		P-ATPase-V	173..1355	CDD:273738	241/1204 (20%)
		E1-E2_ATPase	381..621	CDD:278548	57/269 (21%)
		Cation_ATPase	<758..813	CDD:289987	12/60 (20%)
		HAD_like	<1087..1137	CDD:304363	20/52 (38%)
SPoCk	NP_001262220.1	ATPase-IIA2_Ca	110..1049	CDD:130585	232/1130 (21%)
		Cation_ATPase_N	112..179	CDD:279080	16/73 (22%)
		E1-E2_ATPase	191..425	CDD:278548	57/269 (21%)
		Cation_ATPase	496..579	CDD:289987	25/143 (17%)
		COG4087	<760..823	CDD:226572	21/62 (34%)
		Cation_ATPase_C	872..1044	CDD:279079	37/158 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438605
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840